MIR34AHG

Summary

MIR34AHG (MIR34A host gene, HGNC:51913) is a long non-coding RNA gene on chromosome 1p36.22.

Predicted to be involved in miRNA-mediated post-transcriptional gene silencing.

Source: NCBI Gene 106614088 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51913
Approved symbol	MIR34AHG
Name	MIR34A host gene
Location	1p36.22
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc34a
Ensembl gene	ENSG00000228526
Ensembl biotype	lncRNA
Entrez	106614088
RNAcentral	URS00008E39B8 — lncRNA, 4173 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000437157, ENST00000632503, ENST00000635405, ENST00000635687, ENST00000701773, ENST00000782879, ENST00000782880, ENST00000782881, ENST00000782882, ENST00000782883, ENST00000782884

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437157 — 3 exons

Exon	Start	End
ENSE00004156343	9183631	9183755
ENSE00004156352	9202579	9202710
ENSE00004156355	9181845	9182295

Expression profiles

Bgee: expression breadth ubiquitous, 181 present calls, max score 91.06.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.7010 / max 50.1962, expressed in 1276 samples.

FANTOM5 promoters (7 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10210	1.0178	573
10212	0.8845	541
10211	0.8680	516
10208	0.4254	214
10209	0.2678	118
10214	0.1207	63
10213	0.1168	65

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tendon of biceps brachii	UBERON:0008188	91.06	silver quality
buccal mucosa cell	CL:0002336	90.03	gold quality
stromal cell of endometrium	CL:0002255	84.00	gold quality
right adrenal gland cortex	UBERON:0035827	82.10	gold quality
right uterine tube	UBERON:0001302	81.92	gold quality
right adrenal gland	UBERON:0001233	81.12	gold quality
epithelial cell of pancreas	CL:0000083	80.84	gold quality
adrenal cortex	UBERON:0001235	80.37	gold quality
left adrenal gland cortex	UBERON:0035825	80.25	gold quality
left adrenal gland	UBERON:0001234	79.97	gold quality
visceral pleura	UBERON:0002401	79.23	silver quality
pancreatic ductal cell	CL:0002079	79.21	silver quality
medial globus pallidus	UBERON:0002477	79.06	gold quality
oviduct epithelium	UBERON:0004804	79.04	gold quality
right ovary	UBERON:0002118	78.63	gold quality
left ovary	UBERON:0002119	78.57	gold quality
esophagus squamous epithelium	UBERON:0006920	78.20	silver quality
descending thoracic aorta	UBERON:0002345	78.19	gold quality
minor salivary gland	UBERON:0001830	78.18	gold quality
thoracic aorta	UBERON:0001515	77.77	gold quality
globus pallidus	UBERON:0001875	77.64	silver quality
ascending aorta	UBERON:0001496	77.60	gold quality
mouth mucosa	UBERON:0003729	77.43	gold quality
adrenal gland	UBERON:0002369	77.31	gold quality
parietal pleura	UBERON:0002400	77.25	silver quality
pylorus	UBERON:0001166	77.09	silver quality
Brodmann (1909) area 23	UBERON:0013554	77.07	silver quality
mucosa of paranasal sinus	UBERON:0005030	76.96	gold quality
bronchial epithelial cell	CL:0002328	76.80	silver quality
bronchus	UBERON:0002185	76.62	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.18

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• miR-34a-5p Inhibits Cell Proliferation, Migration and Invasion Through Targeting JAG1/Notch1 Pathway in HPV-Infected Human Epidermal Keratinocytes. (PMID:31781973)
• Identification of microRNA expression signature for the diagnosis and prognosis of cervical squamous cell carcinoma. (PMID:32841775)
• Identification of miRNA-34a and miRNA-155 as prognostic markers for mantle cell lymphoma. (PMID:34024195)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.