MIR3659HG

Summary

MIR3659HG (MIR3659 host gene, HGNC:54306) is a long non-coding RNA gene on chromosome 1p34.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54306
Approved symbol	MIR3659HG
Name	MIR3659 host gene
Location	1p34.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.15
Ensembl gene	ENSG00000224592
Ensembl biotype	lncRNA
Entrez	105378653
RNAcentral	URS0001BBE517 — lncRNA, 1369 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000428151, ENST00000432922, ENST00000792356, ENST00000792357, ENST00000792358, ENST00000792359, ENST00000792360, ENST00000792361, ENST00000792362, ENST00000792363, ENST00000792364, ENST00000792365, ENST00000792366, ENST00000792367, ENST00000792368, ENST00000792369, ENST00000792370

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428151 — 5 exons

Exon	Start	End
ENSE00001729520	38102417	38102496
ENSE00001772149	38103546	38103661
ENSE00004174272	38118960	38119530
ENSE00004174278	38047362	38047614
ENSE00004174279	38105632	38105752

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 82.00.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4395 / max 24.1903, expressed in 176 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
2241	0.4395	176

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skin of abdomen	UBERON:0001416	82.00	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.09	gold quality
zone of skin	UBERON:0000014	80.60	gold quality
skin of leg	UBERON:0001511	79.50	gold quality
nucleus accumbens	UBERON:0001882	77.79	gold quality
caudate nucleus	UBERON:0001873	76.57	gold quality
putamen	UBERON:0001874	75.85	gold quality
anterior cingulate cortex	UBERON:0009835	72.77	gold quality
sural nerve	UBERON:0015488	71.70	gold quality
ganglionic eminence	UBERON:0004023	71.45	gold quality
right frontal lobe	UBERON:0002810	71.17	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.01	gold quality
cerebral cortex	UBERON:0000956	69.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.64	gold quality
frontal cortex	UBERON:0001870	69.03	gold quality
Ammon’s horn	UBERON:0001954	68.04	gold quality
superior frontal gyrus	UBERON:0002661	67.59	gold quality
esophagus mucosa	UBERON:0002469	67.37	gold quality
prefrontal cortex	UBERON:0000451	67.24	gold quality
brain	UBERON:0000955	67.24	gold quality
cortical plate	UBERON:0005343	67.23	gold quality
tibial nerve	UBERON:0001323	66.29	gold quality
amygdala	UBERON:0001876	65.99	gold quality
temporal lobe	UBERON:0001871	65.86	gold quality
ventricular zone	UBERON:0003053	64.87	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.41	gold quality
primary visual cortex	UBERON:0002436	63.85	gold quality
substantia nigra	UBERON:0002038	63.19	gold quality
monocyte	CL:0000576	61.51	gold quality
lower esophagus mucosa	UBERON:0035834	61.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.