MIR3671

Summary

MIR3671 (microRNA 3671, HGNC:38925) is a microRNA gene on chromosome 1p31.3.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100500854 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38925
Approved symbol	MIR3671
Name	microRNA 3671
Location	1p31.3
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3671
Ensembl gene	ENSG00000265996
Ensembl biotype	miRNA
Entrez	100500854
RNAcentral	URS000075A44B — ncRNA, 88 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000580455

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000580455 — 1 exons

Exon	Start	End
ENSE00002731146	65057755	65057842

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 92.54.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	92.54	gold quality
vermiform appendix	UBERON:0001154	88.81	gold quality
bone marrow	UBERON:0002371	88.53	gold quality
skeletal muscle tissue	UBERON:0001134	87.51	gold quality
corpus callosum	UBERON:0002336	87.04	gold quality
right ovary	UBERON:0002118	86.65	gold quality
right coronary artery	UBERON:0001625	86.33	gold quality
left uterine tube	UBERON:0001303	84.85	gold quality
ovary	UBERON:0000992	84.55	gold quality
adrenal tissue	UBERON:0018303	84.39	gold quality
blood	UBERON:0000178	84.16	gold quality
left ovary	UBERON:0002119	84.03	gold quality
endometrium	UBERON:0001295	83.93	gold quality
duodenum	UBERON:0002114	83.43	gold quality
muscle of leg	UBERON:0001383	82.74	gold quality
tibial nerve	UBERON:0001323	82.47	gold quality
endocervix	UBERON:0000458	82.46	gold quality
tibial artery	UBERON:0007610	82.08	gold quality
fundus of stomach	UBERON:0001160	82.07	gold quality
popliteal artery	UBERON:0002250	81.99	gold quality
descending thoracic aorta	UBERON:0002345	81.74	gold quality
myometrium	UBERON:0001296	81.38	gold quality
gastrocnemius	UBERON:0001388	81.24	gold quality
body of uterus	UBERON:0009853	81.11	gold quality
monocyte	CL:0000576	80.99	gold quality
placenta	UBERON:0001987	80.65	gold quality
stomach	UBERON:0000945	80.35	gold quality
body of pancreas	UBERON:0001150	80.01	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	79.87	gold quality
pancreas	UBERON:0001264	79.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.