MIR3672

Summary

MIR3672 (microRNA 3672, HGNC:38957) is a microRNA gene on chromosome Xq24.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100500869 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38957
Approved symbol	MIR3672
Name	microRNA 3672
Location	Xq24
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3672
Ensembl gene	ENSG00000265456
Ensembl biotype	miRNA
Entrez	100500869
RNAcentral	URS000075A6BA — miRNA, 82 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000584290

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000584290 — 1 exons

Exon	Start	End
ENSE00002728547	121370972	121371053

Expression profiles

Bgee: expression breadth broad, 17 present calls, max score 79.37.

Top tissues by expression

17 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	79.37	gold quality
endometrium	UBERON:0001295	78.60	gold quality
stomach	UBERON:0000945	71.71	gold quality
adult mammalian kidney	UBERON:0000082	70.94	gold quality
liver	UBERON:0002107	67.50	gold quality
omental fat pad	UBERON:0010414	66.94	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.42	gold quality
body of pancreas	UBERON:0001150	62.97	gold quality
nucleus accumbens	UBERON:0001882	62.13	gold quality
tibial nerve	UBERON:0001323	59.66	gold quality
muscle layer of sigmoid colon	UBERON:0035805	59.13	gold quality
left lobe of thyroid gland	UBERON:0001120	57.98	gold quality
left ovary	UBERON:0002119	56.45	gold quality
Ammon’s horn	UBERON:0001954	55.63	gold quality
corpus callosum	UBERON:0002336	54.91	gold quality
colon	UBERON:0001155	52.77	gold quality
left testis	UBERON:0004533	41.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.