MIR3681HG

Summary

MIR3681HG (MIR3681 host gene, HGNC:52001) is a long non-coding RNA gene on chromosome 2p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52001
Approved symbol	MIR3681HG
Name	MIR3681 host gene
Location	2p24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224184
Ensembl biotype	lncRNA
Entrez	100506457
RNAcentral	URS0000759F52 — lncRNA, 2195 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 55 — 55 lncRNA

ENST00000412294, ENST00000412606, ENST00000429878, ENST00000438292, ENST00000449986, ENST00000450916, ENST00000451644, ENST00000653212, ENST00000653433, ENST00000653484, ENST00000654108, ENST00000664018, ENST00000665021, ENST00000665111, ENST00000667283, ENST00000701891, ENST00000702500, ENST00000824630, ENST00000824631, ENST00000824632, ENST00000824633, ENST00000824634, ENST00000824635, ENST00000824636, ENST00000824637, ENST00000824638, ENST00000824639, ENST00000824640, ENST00000824641, ENST00000839794, ENST00000840287, ENST00000840288, ENST00000840289, ENST00000840290, ENST00000840291, ENST00000840292, ENST00000840293, ENST00000840294, ENST00000840295, ENST00000840296, ENST00000840297, ENST00000840298, ENST00000840299, ENST00000840300, ENST00000840301, ENST00000840302, ENST00000840303, ENST00000840304, ENST00000840305, ENST00000840306, ENST00000840307, ENST00000840308, ENST00000840309, ENST00000842234, ENST00000842235

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412294 — 6 exons

Exon	Start	End
ENSE00001695822	12166738	12166855
ENSE00001735980	12558206	12558444
ENSE00001771709	12007747	12007843
ENSE00001778919	12576817	12578348
ENSE00001783545	12308688	12308784
ENSE00004234063	12007118	12007227

Expression profiles

Bgee: expression breadth ubiquitous, 149 present calls, max score 89.61.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5311 / max 170.3623, expressed in 116 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
18926	0.2445	55
18931	0.1377	44
18934	0.1063	15
18930	0.0346	14
18923	0.0080	4

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.61	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.53	gold quality
lymph node	UBERON:0000029	70.81	gold quality
bone marrow cell	CL:0002092	67.69	silver quality
right testis	UBERON:0004534	67.34	gold quality
left testis	UBERON:0004533	67.17	gold quality
testis	UBERON:0000473	65.13	gold quality
secondary oocyte	CL:0000655	64.62	silver quality
cortical plate	UBERON:0005343	64.23	gold quality
ventricular zone	UBERON:0003053	62.32	gold quality
sperm	CL:0000019	62.13	silver quality
vermiform appendix	UBERON:0001154	60.44	gold quality
tonsil	UBERON:0002372	60.25	gold quality
buccal mucosa cell	CL:0002336	60.19	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	60.01	gold quality
ganglionic eminence	UBERON:0004023	59.35	gold quality
prefrontal cortex	UBERON:0000451	58.54	gold quality
caecum	UBERON:0001153	58.32	gold quality
endothelial cell	CL:0000115	57.00	gold quality
left ovary	UBERON:0002119	56.69	gold quality
leukocyte	CL:0000738	56.68	gold quality
monocyte	CL:0000576	56.35	gold quality
left adrenal gland cortex	UBERON:0035825	55.74	gold quality
tendon of biceps brachii	UBERON:0008188	55.72	gold quality
left adrenal gland	UBERON:0001234	55.36	gold quality
mucosa of paranasal sinus	UBERON:0005030	55.19	gold quality
right adrenal gland cortex	UBERON:0035827	54.88	gold quality
metanephros cortex	UBERON:0010533	54.84	gold quality
right adrenal gland	UBERON:0001233	54.82	gold quality
stromal cell of endometrium	CL:0002255	54.65	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.