MIR3929

Summary

MIR3929 (microRNA 3929, HGNC:38945) is a microRNA gene on chromosome 18q12.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100500864 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38945
Approved symbol	MIR3929
Name	microRNA 3929
Location	18q12.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3929
Ensembl gene	ENSG00000265641
Ensembl biotype	miRNA
Entrez	100500864
RNAcentral	URS000075A325 — ncRNA, 55 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000584497

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000584497 — 1 exons

Exon	Start	End
ENSE00002729147	35934088	35934142

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 77.77.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	77.77	gold quality
gastrocnemius	UBERON:0001388	74.54	gold quality
blood	UBERON:0000178	73.80	gold quality
granulocyte	CL:0000094	73.00	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.99	gold quality
lymph node	UBERON:0000029	71.80	gold quality
placenta	UBERON:0001987	70.72	gold quality
islet of Langerhans	UBERON:0000006	70.08	gold quality
rectum	UBERON:0001052	69.95	gold quality
adult mammalian kidney	UBERON:0000082	69.88	gold quality
stomach	UBERON:0000945	69.47	gold quality
monocyte	CL:0000576	68.34	gold quality
tibial artery	UBERON:0007610	68.04	gold quality
myometrium	UBERON:0001296	67.93	gold quality
heart left ventricle	UBERON:0002084	66.35	gold quality
putamen	UBERON:0001874	65.81	gold quality
ascending aorta	UBERON:0001496	65.58	gold quality
thoracic mammary gland	UBERON:0005200	65.31	gold quality
body of stomach	UBERON:0001161	64.85	gold quality
left adrenal gland cortex	UBERON:0035825	64.76	gold quality
right adrenal gland cortex	UBERON:0035827	64.58	gold quality
hypothalamus	UBERON:0001898	64.53	gold quality
right adrenal gland	UBERON:0001233	64.34	gold quality
heart	UBERON:0000948	64.32	gold quality
Ammon’s horn	UBERON:0001954	64.04	gold quality
upper lobe of left lung	UBERON:0008952	62.93	gold quality
body of pancreas	UBERON:0001150	62.82	gold quality
subcutaneous adipose tissue	UBERON:0002190	62.09	gold quality
esophagus mucosa	UBERON:0002469	61.87	gold quality
skin of abdomen	UBERON:0001416	61.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• miR-3929 Inhibits Proliferation and Promotes Apoptosis by Downregulating Cripto-1 Expression in Cervical Cancer Cells. (PMID:34569498)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.