MIR3942

Summary

MIR3942 (microRNA 3942, HGNC:38976) is a microRNA gene on chromosome 15q14.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100500904 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38976
Approved symbol	MIR3942
Name	microRNA 3942
Location	15q14
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3942
Ensembl gene	ENSG00000265102
Ensembl biotype	miRNA
Entrez	100500904
RNAcentral	URS000075A35A — miRNA, 109 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000585264

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000585264 — 1 exons

Exon	Start	End
ENSE00002693968	35372256	35372364

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 90.10.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
olfactory segment of nasal mucosa	UBERON:0005386	90.10	gold quality
right uterine tube	UBERON:0001302	88.56	gold quality
sural nerve	UBERON:0015488	84.63	gold quality
adrenal tissue	UBERON:0018303	82.63	gold quality
body of pancreas	UBERON:0001150	81.28	gold quality
left lobe of thyroid gland	UBERON:0001120	80.56	gold quality
left ovary	UBERON:0002119	80.43	gold quality
pancreas	UBERON:0001264	80.40	gold quality
ovary	UBERON:0000992	79.82	gold quality
right ovary	UBERON:0002118	79.66	gold quality
calcaneal tendon	UBERON:0003701	79.66	gold quality
thyroid gland	UBERON:0002046	79.26	gold quality
kidney	UBERON:0002113	79.19	gold quality
endometrium	UBERON:0001295	79.13	gold quality
liver	UBERON:0002107	79.08	gold quality
body of uterus	UBERON:0009853	79.07	gold quality
monocyte	CL:0000576	78.93	gold quality
duodenum	UBERON:0002114	78.80	gold quality
myometrium	UBERON:0001296	78.71	gold quality
right lobe of liver	UBERON:0001114	78.55	gold quality
stomach	UBERON:0000945	78.13	gold quality
right lobe of thyroid gland	UBERON:0001119	77.99	gold quality
metanephros cortex	UBERON:0010533	77.92	gold quality
tibial nerve	UBERON:0001323	77.90	gold quality
vagina	UBERON:0000996	77.74	gold quality
endocervix	UBERON:0000458	77.65	gold quality
minor salivary gland	UBERON:0001830	77.37	gold quality
placenta	UBERON:0001987	77.34	gold quality
saliva-secreting gland	UBERON:0001044	77.33	gold quality
body of stomach	UBERON:0001161	77.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.