MIR3945HG

Summary

MIR3945HG (MIR3945 host gene, HGNC:52002) is a long non-coding RNA gene on chromosome 4q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52002
Approved symbol	MIR3945HG
Name	MIR3945 host gene
Location	4q35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251230
Ensembl biotype	lncRNA
Entrez	731424
RNAcentral	URS00025E802B — lncRNA, 2081 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000510284, ENST00000511703, ENST00000656525, ENST00000659446, ENST00000665689, ENST00000701617, ENST00000841726, ENST00000841727, ENST00000841728, ENST00000841729, ENST00000841730, ENST00000841731

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510284 — 3 exons

Exon	Start	End
ENSE00002066812	184850495	184850599
ENSE00004266233	184846058	184846534
ENSE00004266239	184855469	184855685

Expression profiles

Bgee: expression breadth ubiquitous, 146 present calls, max score 84.30.

FANTOM5 (CAGE): breadth broad, TPM avg 10.3801 / max 1204.7344, expressed in 290 samples.

FANTOM5 promoters (11 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55219	4.3828	184
55218	2.8411	144
55220	1.2786	107
55209	0.6362	110
55201	0.3642	118
55210	0.3588	88
55217	0.3299	76
55211	0.0616	38
55216	0.0549	18
55221	0.0438	19

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	84.30	gold quality
buccal mucosa cell	CL:0002336	77.09	silver quality
blood	UBERON:0000178	75.88	gold quality
lower lobe of lung	UBERON:0008949	71.57	gold quality
granulocyte	CL:0000094	71.43	gold quality
leukocyte	CL:0000738	71.02	gold quality
monocyte	CL:0000576	71.01	gold quality
bone marrow	UBERON:0002371	69.06	gold quality
oocyte	CL:0000023	67.02	silver quality
vermiform appendix	UBERON:0001154	66.63	gold quality
upper lobe of lung	UBERON:0008948	66.41	gold quality
upper lobe of left lung	UBERON:0008952	66.39	gold quality
right lung	UBERON:0002167	65.82	gold quality
sural nerve	UBERON:0015488	65.78	silver quality
lung	UBERON:0002048	64.63	gold quality
gingival epithelium	UBERON:0001949	64.32	gold quality
ventricular zone	UBERON:0003053	62.89	gold quality
esophagus squamous epithelium	UBERON:0006920	62.09	gold quality
amniotic fluid	UBERON:0000173	61.82	gold quality
caecum	UBERON:0001153	60.91	gold quality
secondary oocyte	CL:0000655	60.25	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.24	gold quality
gastrocnemius	UBERON:0001388	59.27	gold quality
muscle of leg	UBERON:0001383	59.17	gold quality
ganglionic eminence	UBERON:0004023	58.80	gold quality
omental fat pad	UBERON:0010414	58.68	gold quality
peritoneum	UBERON:0002358	58.63	gold quality
spleen	UBERON:0002106	58.41	gold quality
adipose tissue of abdominal region	UBERON:0007808	57.71	gold quality
calcaneal tendon	UBERON:0003701	57.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	15.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.