MIR4280HG

Summary

MIR4280HG (MIR4280 host gene, HGNC:54975) is a long non-coding RNA gene on chromosome 5q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54975
Approved symbol	MIR4280HG
Name	MIR4280 host gene
Location	5q14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233828
Ensembl biotype	lncRNA
Entrez	117751736
RNAcentral	URS00026A25EC — lncRNA, 2434 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000655245, ENST00000662995, ENST00000666497, ENST00000748825, ENST00000748826, ENST00000748827, ENST00000748828, ENST00000748829, ENST00000748830, ENST00000748831, ENST00000748832, ENST00000748833, ENST00000748834, ENST00000748835, ENST00000748836, ENST00000748837, ENST00000748838

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000655245 — 2 exons

Exon	Start	End
ENSE00003858378	87049227	87050964
ENSE00003875445	87055250	87058694

Expression profiles

Bgee: expression breadth broad, 90 present calls, max score 80.63.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0212 / max 2.0501, expressed in 11 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
62408	0.0212	11

Top tissues by expression

185 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.63	silver quality
colonic epithelium	UBERON:0000397	65.21	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	63.73	gold quality
spinal cord	UBERON:0002240	61.50	gold quality
ganglionic eminence	UBERON:0004023	58.14	gold quality
prefrontal cortex	UBERON:0000451	57.97	gold quality
substantia nigra	UBERON:0002038	57.09	gold quality
granulocyte	CL:0000094	56.02	gold quality
midbrain	UBERON:0001891	55.05	gold quality
putamen	UBERON:0001874	54.07	gold quality
amygdala	UBERON:0001876	52.61	gold quality
hypothalamus	UBERON:0001898	52.43	gold quality
lower lobe of lung	UBERON:0008949	52.10	silver quality
blood	UBERON:0000178	51.81	gold quality
stromal cell of endometrium	CL:0002255	51.76	silver quality
corpus callosum	UBERON:0002336	51.29	gold quality
monocyte	CL:0000576	51.24	silver quality
frontal cortex	UBERON:0001870	51.21	gold quality
gall bladder	UBERON:0002110	50.84	gold quality
spleen	UBERON:0002106	50.71	gold quality
Ammon’s horn	UBERON:0001954	50.64	gold quality
Brodmann (1909) area 9	UBERON:0013540	50.43	gold quality
neocortex	UBERON:0001950	50.14	gold quality
lymph node	UBERON:0000029	49.94	gold quality
primary visual cortex	UBERON:0002436	49.26	gold quality
caudate nucleus	UBERON:0001873	49.13	gold quality
calcaneal tendon	UBERON:0003701	48.74	silver quality
forebrain	UBERON:0001890	48.73	gold quality
brain	UBERON:0000955	48.69	gold quality
cerebral cortex	UBERON:0000956	48.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.