MIR4300HG

Summary

MIR4300HG (MIR4300 host gene, HGNC:52003) is a long non-coding RNA gene on chromosome 11q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52003
Approved symbol	MIR4300HG
Name	MIR4300 host gene
Location	11q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245832
Ensembl biotype	lncRNA
Entrez	101928989
RNAcentral	URS000075B57A — lncRNA, 1400 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000500502, ENST00000530896, ENST00000532217, ENST00000653173, ENST00000655084, ENST00000659248, ENST00000661273, ENST00000662673, ENST00000666803, ENST00000667990, ENST00000668723, ENST00000668951, ENST00000671244, ENST00000671287, ENST00000816596

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500502 — 8 exons

Exon	Start	End
ENSE00001441101	82099974	82100207
ENSE00001959999	81879854	81880167
ENSE00001969981	82356512	82356628
ENSE00001971519	82096461	82096608
ENSE00001973093	81882154	81882296
ENSE00001983126	82015608	82015734
ENSE00001984783	82349926	82350004
ENSE00001987227	82403679	82403913

Expression profiles

Bgee: expression breadth ubiquitous, 145 present calls, max score 77.61.

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.61	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.11	gold quality
left testis	UBERON:0004533	68.22	gold quality
right testis	UBERON:0004534	67.07	gold quality
testis	UBERON:0000473	66.70	gold quality
cortical plate	UBERON:0005343	65.96	gold quality
ganglionic eminence	UBERON:0004023	64.79	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.02	silver quality
sperm	CL:0000019	56.87	silver quality
left ovary	UBERON:0002119	56.73	gold quality
corpus callosum	UBERON:0002336	56.35	gold quality
substantia nigra pars reticulata	UBERON:0001966	56.20	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.83	gold quality
smooth muscle tissue	UBERON:0001135	55.51	gold quality
mucosa of stomach	UBERON:0001199	55.18	gold quality
stromal cell of endometrium	CL:0002255	54.82	silver quality
right ovary	UBERON:0002118	54.64	gold quality
spinal cord	UBERON:0002240	54.39	gold quality
right adrenal gland cortex	UBERON:0035827	54.15	gold quality
tibial artery	UBERON:0007610	54.09	gold quality
monocyte	CL:0000576	54.08	gold quality
popliteal artery	UBERON:0002250	54.02	gold quality
prefrontal cortex	UBERON:0000451	53.98	gold quality
leukocyte	CL:0000738	53.94	gold quality
ovary	UBERON:0000992	53.21	gold quality
lateral globus pallidus	UBERON:0002476	53.08	gold quality
upper leg skin	UBERON:0004262	52.38	silver quality
aorta	UBERON:0000947	52.18	gold quality
hypothalamus	UBERON:0001898	52.03	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.98	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-GEOD-180759	yes	3341.44
E-ANND-3	yes	3.74

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study. (PMID:32928300)
• Genetic variant of MIR4300HG is associated with progression of adolescent idiopathic scoliosis in a Chinese population. (PMID:33985553)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.