MIR4432HG
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Summary
MIR4432HG (MIR4432 host gene, HGNC:52005) is a long non-coding RNA gene on chromosome 2p16.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:52005 |
| Approved symbol | MIR4432HG |
| Name | MIR4432 host gene |
| Location | 2p16.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000228590 |
| Ensembl biotype | lncRNA |
| Entrez | 106660609 |
| RNAcentral | URS00008E39B6 — lncRNA, 974 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 50 — 50 lncRNA
ENST00000441598, ENST00000453476, ENST00000457668, ENST00000647917, ENST00000650395, ENST00000686152, ENST00000692549, ENST00000702294, ENST00000730613, ENST00000730614, ENST00000730615, ENST00000730616, ENST00000730617, ENST00000730618, ENST00000730619, ENST00000730620, ENST00000730621, ENST00000730622, ENST00000730623, ENST00000730624, ENST00000730625, ENST00000730626, ENST00000730627, ENST00000730628, ENST00000730629, ENST00000730630, ENST00000730631, ENST00000730632, ENST00000730633, ENST00000730634, ENST00000730635, ENST00000730636, ENST00000730637, ENST00000730638, ENST00000730639, ENST00000730640, ENST00000730641, ENST00000730642, ENST00000730643, ENST00000730644, ENST00000730645, ENST00000730646, ENST00000730647, ENST00000730648, ENST00000730649, ENST00000730650, ENST00000730651, ENST00000730652, ENST00000730653, ENST00000730654
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000441598 — 8 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001627883 | 60359270 | 60359848 |
| ENSE00001760935 | 60369909 | 60370037 |
| ENSE00001766337 | 60382944 | 60383036 |
| ENSE00001768959 | 60378502 | 60378620 |
| ENSE00003835298 | 60342817 | 60342996 |
| ENSE00003837026 | 60343088 | 60343168 |
| ENSE00003837519 | 60351809 | 60352308 |
| ENSE00003840966 | 60340166 | 60340238 |
Expression profiles
Bgee: expression breadth broad, 73 present calls, max score 69.90.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0458 / max 10.1014, expressed in 24 samples.
FANTOM5 promoters (2 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 28578 | 0.0368 | 21 |
| 28571 | 0.0091 | 4 |
Top tissues by expression
73 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| lymph node | UBERON:0000029 | 69.90 | gold quality |
| bone marrow cell | CL:0002092 | 68.28 | silver quality |
| tonsil | UBERON:0002372 | 66.95 | gold quality |
| right atrium auricular region | UBERON:0006631 | 66.34 | gold quality |
| granulocyte | CL:0000094 | 65.54 | gold quality |
| heart | UBERON:0000948 | 64.16 | gold quality |
| bone marrow | UBERON:0002371 | 63.83 | gold quality |
| heart left ventricle | UBERON:0002084 | 62.92 | gold quality |
| vermiform appendix | UBERON:0001154 | 61.65 | gold quality |
| leukocyte | CL:0000738 | 61.04 | gold quality |
| monocyte | CL:0000576 | 60.34 | gold quality |
| cortical plate | UBERON:0005343 | 59.94 | gold quality |
| ventricular zone | UBERON:0003053 | 58.14 | silver quality |
| ganglionic eminence | UBERON:0004023 | 56.81 | silver quality |
| urinary bladder | UBERON:0001255 | 56.14 | gold quality |
| blood | UBERON:0000178 | 55.89 | gold quality |
| anterior cingulate cortex | UBERON:0009835 | 54.86 | gold quality |
| apex of heart | UBERON:0002098 | 54.70 | gold quality |
| skin of leg | UBERON:0001511 | 53.76 | gold quality |
| pancreas | UBERON:0001264 | 52.83 | gold quality |
| prefrontal cortex | UBERON:0000451 | 52.58 | gold quality |
| zone of skin | UBERON:0000014 | 52.11 | gold quality |
| multicellular organism | UBERON:0000468 | 52.10 | gold quality |
| placenta | UBERON:0001987 | 52.04 | gold quality |
| gall bladder | UBERON:0002110 | 50.79 | gold quality |
| spleen | UBERON:0002106 | 50.67 | gold quality |
| adrenal gland | UBERON:0002369 | 49.68 | gold quality |
| stomach | UBERON:0000945 | 49.54 | gold quality |
| skin of abdomen | UBERON:0001416 | 49.27 | gold quality |
| islet of Langerhans | UBERON:0000006 | 49.04 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 5.84 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): cerebral amyloid angiopathy