MIR4500HG

Summary

MIR4500HG (MIR4500 host gene, HGNC:42773) is a long non-coding RNA gene on chromosome 13q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42773
Approved symbol	MIR4500HG
Name	MIR4500 host gene
Location	13q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228824
Ensembl biotype	lncRNA
Entrez	642345
RNAcentral	URS00002172B5 — lncRNA, 1675 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 65 — 65 lncRNA

ENST00000436290, ENST00000441617, ENST00000453832, ENST00000606590, ENST00000607309, ENST00000654568, ENST00000656150, ENST00000656584, ENST00000658012, ENST00000658270, ENST00000658487, ENST00000660424, ENST00000662489, ENST00000667327, ENST00000668242, ENST00000668555, ENST00000668695, ENST00000668840, ENST00000684896, ENST00000685035, ENST00000717729, ENST00000717730, ENST00000717731, ENST00000717732, ENST00000717733, ENST00000834943, ENST00000834944, ENST00000834945, ENST00000834946, ENST00000834947, ENST00000834948, ENST00000834949, ENST00000834950, ENST00000834951, ENST00000834952, ENST00000834953, ENST00000834954, ENST00000834955, ENST00000834956, ENST00000834957, ENST00000834958, ENST00000834959, ENST00000834960, ENST00000834961, ENST00000834962, ENST00000834963, ENST00000834964, ENST00000834965, ENST00000834966, ENST00000834967, ENST00000834968, ENST00000834969, ENST00000834970, ENST00000834971, ENST00000834972, ENST00000834973, ENST00000834974, ENST00000834975, ENST00000834976, ENST00000834977, ENST00000834978, ENST00000834979, ENST00000834980, ENST00000834981, ENST00000834982

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436290 — 6 exons

Exon	Start	End
ENSE00001629742	87460924	87460969
ENSE00001674484	87670836	87670963
ENSE00001709232	87443987	87445130
ENSE00001735343	87447096	87447233
ENSE00004033277	87511366	87511470
ENSE00004033287	87473440	87473553

Expression profiles

Bgee: expression breadth ubiquitous, 142 present calls, max score 80.43.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4896 / max 100.4753, expressed in 119 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
137780	0.1552	63
137778	0.1355	57
137779	0.1225	56
137777	0.0764	37

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
secondary oocyte	CL:0000655	80.43	gold quality
sural nerve	UBERON:0015488	79.38	gold quality
prefrontal cortex	UBERON:0000451	76.62	gold quality
anterior cingulate cortex	UBERON:0009835	76.12	gold quality
cortical plate	UBERON:0005343	76.05	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.74	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.97	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.74	gold quality
right frontal lobe	UBERON:0002810	70.59	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	70.37	gold quality
tibial nerve	UBERON:0001323	70.25	gold quality
neocortex	UBERON:0001950	69.34	gold quality
buccal mucosa cell	CL:0002336	68.68	gold quality
frontal cortex	UBERON:0001870	68.41	gold quality
amygdala	UBERON:0001876	67.62	gold quality
right uterine tube	UBERON:0001302	66.76	gold quality
cerebral cortex	UBERON:0000956	65.73	gold quality
nucleus accumbens	UBERON:0001882	64.26	gold quality
hypothalamus	UBERON:0001898	64.26	gold quality
ganglionic eminence	UBERON:0004023	64.12	gold quality
ventricular zone	UBERON:0003053	64.02	gold quality
forebrain	UBERON:0001890	61.88	gold quality
right lobe of liver	UBERON:0001114	61.77	gold quality
mucosa of transverse colon	UBERON:0004991	61.06	gold quality
substantia nigra	UBERON:0002038	60.86	gold quality
Ammon’s horn	UBERON:0001954	60.29	gold quality
oocyte	CL:0000023	60.27	silver quality
brain	UBERON:0000955	60.16	gold quality
caudate nucleus	UBERON:0001873	60.13	gold quality
putamen	UBERON:0001874	59.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.