MIR4795

Summary

MIR4795 (microRNA 4795, HGNC:41757) is a microRNA gene on chromosome 3p11.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100616161 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41757
Approved symbol	MIR4795
Name	microRNA 4795
Location	3p11.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-4795
Ensembl gene	ENSG00000264119
Ensembl biotype	miRNA
Entrez	100616161
RNAcentral	URS000075C440 — miRNA, 89 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000584182

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000584182 — 1 exons

Exon	Start	End
ENSE00002727024	87226189	87226277

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 75.79.

Top tissues by expression

54 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	75.79	gold quality
gastrocnemius	UBERON:0001388	72.36	gold quality
endometrium	UBERON:0001295	72.28	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.15	gold quality
right atrium auricular region	UBERON:0006631	71.92	gold quality
urinary bladder	UBERON:0001255	70.99	gold quality
lymph node	UBERON:0000029	70.71	gold quality
placenta	UBERON:0001987	69.76	gold quality
tibial artery	UBERON:0007610	69.71	gold quality
body of stomach	UBERON:0001161	69.19	gold quality
substantia nigra	UBERON:0002038	69.00	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.86	gold quality
transverse colon	UBERON:0001157	67.61	gold quality
Ammon’s horn	UBERON:0001954	67.46	gold quality
body of pancreas	UBERON:0001150	67.33	gold quality
ascending aorta	UBERON:0001496	66.84	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.75	gold quality
colon	UBERON:0001155	66.25	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.19	gold quality
skin of leg	UBERON:0001511	65.20	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.09	gold quality
esophagus	UBERON:0001043	64.87	gold quality
upper lobe of left lung	UBERON:0008952	64.78	gold quality
body of uterus	UBERON:0009853	64.51	gold quality
skin of abdomen	UBERON:0001416	64.46	gold quality
small intestine Peyer’s patch	UBERON:0003454	64.33	gold quality
esophagus mucosa	UBERON:0002469	64.24	gold quality
right ovary	UBERON:0002118	64.05	gold quality
omental fat pad	UBERON:0010414	63.60	gold quality
subcutaneous adipose tissue	UBERON:0002190	63.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.