MIR4802

Summary

MIR4802 (microRNA 4802, HGNC:41658) is a microRNA gene on chromosome 4p14.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100616274 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41658
Approved symbol	MIR4802
Name	microRNA 4802
Location	4p14
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-4802
Ensembl gene	ENSG00000263642
Ensembl biotype	miRNA
Entrez	100616274
RNAcentral	URS000075EA36 — miRNA, 80 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000581881

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000581881 — 1 exons

Exon	Start	End
ENSE00002716771	40502040	40502119

Expression profiles

Bgee: expression breadth broad, 57 present calls, max score 93.50.

Top tissues by expression

57 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	93.50	gold quality
kidney	UBERON:0002113	87.92	gold quality
myometrium	UBERON:0001296	84.32	gold quality
adult mammalian kidney	UBERON:0000082	84.02	gold quality
liver	UBERON:0002107	83.52	gold quality
bone marrow	UBERON:0002371	82.80	gold quality
blood	UBERON:0000178	82.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.32	gold quality
sural nerve	UBERON:0015488	80.96	gold quality
stomach	UBERON:0000945	79.02	gold quality
heart	UBERON:0000948	77.42	gold quality
monocyte	CL:0000576	75.55	gold quality
islet of Langerhans	UBERON:0000006	74.79	gold quality
multicellular organism	UBERON:0000468	73.37	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.93	gold quality
right atrium auricular region	UBERON:0006631	71.69	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.51	gold quality
intestine	UBERON:0000160	70.63	gold quality
gastrocnemius	UBERON:0001388	70.62	gold quality
endometrium	UBERON:0001295	70.57	gold quality
colon	UBERON:0001155	69.09	gold quality
tibial nerve	UBERON:0001323	69.09	gold quality
left adrenal gland	UBERON:0001234	68.30	gold quality
left adrenal gland cortex	UBERON:0035825	68.10	gold quality
body of stomach	UBERON:0001161	68.05	gold quality
lung	UBERON:0002048	67.46	gold quality
right adrenal gland	UBERON:0001233	66.56	gold quality
body of uterus	UBERON:0009853	66.46	gold quality
transverse colon	UBERON:0001157	66.22	gold quality
right adrenal gland cortex	UBERON:0035827	65.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.