MIR493HG

Summary

MIR493HG (MIR493 cluster host gene, HGNC:55978) is a long non-coding RNA gene on chromosome 14q32.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55978
Approved symbol	MIR493HG
Name	MIR493 cluster host gene
Location	14q32.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258399
Ensembl biotype	lncRNA
Entrez	123466208
RNAcentral	URS0000A77C2C — lncRNA, 1985 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000637474, ENST00000742328

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000637474 — 19 exons

Exon	Start	End
ENSE00003791882	100906098	100906163
ENSE00003792202	100947034	100947194
ENSE00003792350	100942762	100942826
ENSE00003792357	100894872	100895039
ENSE00003794245	100940365	100940450
ENSE00003794368	100897593	100897732
ENSE00003794530	100889649	100889756
ENSE00003794781	100936178	100936310
ENSE00003794876	100937403	100937488
ENSE00003795366	100944809	100944925
ENSE00003795517	100935772	100935881
ENSE00003795648	100938880	100938956
ENSE00003795812	100913432	100913521
ENSE00003796451	100906936	100907132
ENSE00003797649	100898957	100899085
ENSE00003799301	100910233	100910304
ENSE00003799816	100845458	100845533
ENSE00003800881	100894699	100894770
ENSE00003800940	100836269	100836300

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 83.50.

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.50	gold quality
adrenal tissue	UBERON:0018303	79.91	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.74	gold quality
calcaneal tendon	UBERON:0003701	65.00	gold quality
sural nerve	UBERON:0015488	62.72	silver quality
skeletal muscle tissue	UBERON:0001134	62.62	silver quality
tonsil	UBERON:0002372	62.44	silver quality
adrenal gland	UBERON:0002369	62.10	gold quality
pituitary gland	UBERON:0000007	61.17	gold quality
right adrenal gland cortex	UBERON:0035827	61.01	gold quality
adenohypophysis	UBERON:0002196	60.79	gold quality
urinary bladder	UBERON:0001255	60.68	silver quality
left adrenal gland cortex	UBERON:0035825	60.38	gold quality
ganglionic eminence	UBERON:0004023	60.03	silver quality
cortex of kidney	UBERON:0001225	59.35	gold quality
right adrenal gland	UBERON:0001233	59.06	gold quality
left adrenal gland	UBERON:0001234	58.94	gold quality
placenta	UBERON:0001987	57.69	gold quality
blood	UBERON:0000178	56.01	gold quality
stromal cell of endometrium	CL:0002255	55.91	gold quality
ovary	UBERON:0000992	54.40	gold quality
left ovary	UBERON:0002119	53.93	gold quality
right ovary	UBERON:0002118	53.37	gold quality
superior frontal gyrus	UBERON:0002661	53.03	gold quality
kidney	UBERON:0002113	52.91	gold quality
muscle of leg	UBERON:0001383	52.63	gold quality
prefrontal cortex	UBERON:0000451	52.24	gold quality
pancreas	UBERON:0001264	51.75	gold quality
hypothalamus	UBERON:0001898	51.29	gold quality
islet of Langerhans	UBERON:0000006	50.90	gold quality

Single-cell (SCXA)

Detected in 5 experiment(s), a significant marker in 4.

Experiment	Marker?	Max mean expression
E-GEOD-180759	yes	5294.05
E-HCAD-35	yes	4110.31
E-HCAD-25	yes	3932.24
E-ANND-3	yes	4.49
E-HCAD-30	no	2155.91

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.