MIR548XHG

Summary

MIR548XHG (MIR548X host gene, HGNC:52006) is a long non-coding RNA gene on chromosome 21q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52006
Approved symbol	MIR548XHG
Name	MIR548X host gene
Location	21q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224141
Ensembl biotype	lncRNA
Entrez	101927797
RNAcentral	URS000075DA0F — lncRNA, 675 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000355189, ENST00000414582, ENST00000437492, ENST00000653218, ENST00000656413, ENST00000671206

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000355189 — 5 exons

Exon	Start	End
ENSE00001518655	18752748	18753116
ENSE00001657136	18561615	18561691
ENSE00001755702	18759774	18759804
ENSE00001764729	18737924	18738025
ENSE00001788014	18589527	18589620

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 85.73.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0556 / max 8.0954, expressed in 33 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189872	0.0556	33

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.73	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.21	gold quality
cortical plate	UBERON:0005343	67.46	gold quality
sural nerve	UBERON:0015488	66.80	silver quality
ventricular zone	UBERON:0003053	65.26	gold quality
bone marrow cell	CL:0002092	65.07	silver quality
skeletal muscle tissue	UBERON:0001134	61.23	silver quality
ganglionic eminence	UBERON:0004023	60.97	gold quality
cortex of kidney	UBERON:0001225	60.94	gold quality
bone marrow	UBERON:0002371	58.43	silver quality
urinary bladder	UBERON:0001255	55.31	gold quality
calcaneal tendon	UBERON:0003701	53.52	gold quality
liver	UBERON:0002107	52.89	gold quality
tonsil	UBERON:0002372	52.88	silver quality
leukocyte	CL:0000738	52.84	gold quality
monocyte	CL:0000576	52.53	gold quality
blood	UBERON:0000178	52.51	gold quality
corpus callosum	UBERON:0002336	52.01	gold quality
vermiform appendix	UBERON:0001154	50.86	gold quality
placenta	UBERON:0001987	50.73	gold quality
prefrontal cortex	UBERON:0000451	50.61	gold quality
lymph node	UBERON:0000029	50.12	gold quality
kidney	UBERON:0002113	49.97	gold quality
islet of Langerhans	UBERON:0000006	49.89	gold quality
primary visual cortex	UBERON:0002436	48.91	silver quality
superior frontal gyrus	UBERON:0002661	48.28	silver quality
muscle of leg	UBERON:0001383	47.35	gold quality
duodenum	UBERON:0002114	47.04	silver quality
gastrocnemius	UBERON:0001388	46.68	gold quality
adult mammalian kidney	UBERON:0000082	46.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.40

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.