MIR600HG

Summary

MIR600HG (MIR600 host gene, HGNC:23642) is a long non-coding RNA gene on chromosome 9q33.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23642
Approved symbol	MIR600HG
Name	MIR600 host gene
Location	9q33.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	GL012, FLJ22161
Ensembl gene	ENSG00000236901
Ensembl biotype	lncRNA
Entrez	81571
RNAcentral	URS000075BA79 — lncRNA, 6002 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000449175, ENST00000545631

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449175 — 1 exons

Exon	Start	End
ENSE00001635621	123109494	123115477

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 87.27.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primary visual cortex	UBERON:0002436	87.27	gold quality
superior frontal gyrus	UBERON:0002661	86.22	gold quality
cortical plate	UBERON:0005343	85.88	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.44	gold quality
right uterine tube	UBERON:0001302	83.15	gold quality
right frontal lobe	UBERON:0002810	83.11	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.04	gold quality
frontal cortex	UBERON:0001870	82.75	gold quality
cerebellum	UBERON:0002037	82.63	gold quality
cerebellar cortex	UBERON:0002129	82.58	gold quality
cerebellar hemisphere	UBERON:0002245	82.53	gold quality
Brodmann (1909) area 9	UBERON:0013540	82.48	gold quality
prefrontal cortex	UBERON:0000451	82.21	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	81.86	gold quality
cerebral cortex	UBERON:0000956	80.39	gold quality
lower esophagus mucosa	UBERON:0035834	79.78	gold quality
anterior cingulate cortex	UBERON:0009835	78.57	gold quality
ganglionic eminence	UBERON:0004023	78.07	gold quality
brain	UBERON:0000955	77.48	gold quality
caudate nucleus	UBERON:0001873	74.89	gold quality
pituitary gland	UBERON:0000007	74.36	gold quality
putamen	UBERON:0001874	74.36	gold quality
nucleus accumbens	UBERON:0001882	74.30	gold quality
esophagus mucosa	UBERON:0002469	74.05	gold quality
apex of heart	UBERON:0002098	73.86	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.84	gold quality
small intestine Peyer’s patch	UBERON:0003454	73.51	gold quality
adenohypophysis	UBERON:0002196	73.09	gold quality
Ammon’s horn	UBERON:0001954	72.71	gold quality
spleen	UBERON:0002106	72.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.33

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• lncRNA MIR600HG induces the proliferation and invasion of colorectal cancer cells via regulating miR-144-3p/KIF3A. (PMID:35378445)
• Long Noncoding RNA MIR600HG Binds to MicroRNA-125a-5p to Prevent Pancreatic Cancer Progression Via Mitochondrial Tumor Suppressor 1-Dependent Suppression of Extracellular Regulated Protein Kinases Signaling Pathway. (PMID:37099789)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.