MIR6792

Summary

MIR6792 (microRNA 6792, HGNC:50054) is a microRNA gene on chromosome 19p13.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465475 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50054
Approved symbol	MIR6792
Name	microRNA 6792
Location	19p13.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6792
Ensembl gene	ENSG00000273657
Ensembl biotype	miRNA
Entrez	102465475
RNAcentral	URS000075B35C — miRNA, 67 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000614460

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000614460 — 1 exons

Exon	Start	End
ENSE00003723937	7617439	7617505

Expression profiles

Bgee: expression breadth broad, 66 present calls, max score 83.16.

Top tissues by expression

66 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle of leg	UBERON:0001383	83.16	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.01	gold quality
adrenal tissue	UBERON:0018303	79.17	gold quality
lower esophagus mucosa	UBERON:0035834	76.26	gold quality
mucosa of transverse colon	UBERON:0004991	74.76	gold quality
skin of abdomen	UBERON:0001416	72.66	gold quality
prefrontal cortex	UBERON:0000451	72.27	gold quality
liver	UBERON:0002107	72.16	gold quality
omental fat pad	UBERON:0010414	71.97	gold quality
right lobe of liver	UBERON:0001114	71.73	gold quality
skin of leg	UBERON:0001511	71.43	gold quality
ectocervix	UBERON:0012249	71.32	gold quality
subcutaneous adipose tissue	UBERON:0002190	70.80	gold quality
stomach	UBERON:0000945	70.61	gold quality
tibial nerve	UBERON:0001323	70.56	gold quality
body of stomach	UBERON:0001161	70.22	gold quality
rectum	UBERON:0001052	70.05	gold quality
tibial artery	UBERON:0007610	69.98	gold quality
endometrium	UBERON:0001295	69.85	gold quality
fundus of stomach	UBERON:0001160	69.76	gold quality
transverse colon	UBERON:0001157	69.39	gold quality
colon	UBERON:0001155	69.29	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.14	gold quality
body of pancreas	UBERON:0001150	68.99	gold quality
muscle layer of sigmoid colon	UBERON:0035805	68.65	gold quality
kidney	UBERON:0002113	68.38	gold quality
intestine	UBERON:0000160	68.37	gold quality
substantia nigra	UBERON:0002038	68.22	gold quality
adult mammalian kidney	UBERON:0000082	68.09	gold quality
lower esophagus muscularis layer	UBERON:0035833	67.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA LINC00930 targeting miR-6792-3p/ZBTB16 regulates the proliferation and EMT of pancreatic cancer. (PMID:38789960)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.