MIR6793

Summary

MIR6793 (microRNA 6793, HGNC:50251) is a microRNA gene on chromosome 19p13.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102466737 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50251
Approved symbol	MIR6793
Name	microRNA 6793
Location	19p13.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6793
Ensembl gene	ENSG00000275640
Ensembl biotype	miRNA
Entrez	102466737
RNAcentral	URS000075BB5A — ncRNA, 63 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000612376

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000612376 — 1 exons

Exon	Start	End
ENSE00003741186	10828973	10829035

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 83.28.

Top tissues by expression

91 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
kidney	UBERON:0002113	83.28	gold quality
bone marrow	UBERON:0002371	81.28	gold quality
adrenal tissue	UBERON:0018303	78.03	gold quality
blood	UBERON:0000178	77.44	gold quality
rectum	UBERON:0001052	77.03	gold quality
monocyte	CL:0000576	76.08	gold quality
right lung	UBERON:0002167	75.83	gold quality
muscle of leg	UBERON:0001383	74.40	gold quality
granulocyte	CL:0000094	73.69	gold quality
urinary bladder	UBERON:0001255	73.53	gold quality
metanephros cortex	UBERON:0010533	73.49	gold quality
islet of Langerhans	UBERON:0000006	73.29	gold quality
gastrocnemius	UBERON:0001388	72.82	gold quality
heart left ventricle	UBERON:0002084	72.32	gold quality
right uterine tube	UBERON:0001302	71.92	gold quality
gall bladder	UBERON:0002110	71.90	gold quality
body of stomach	UBERON:0001161	71.60	gold quality
lymph node	UBERON:0000029	71.50	gold quality
stomach	UBERON:0000945	71.30	gold quality
heart	UBERON:0000948	71.19	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.16	gold quality
liver	UBERON:0002107	71.05	gold quality
endometrium	UBERON:0001295	71.01	gold quality
apex of heart	UBERON:0002098	71.01	gold quality
right lobe of liver	UBERON:0001114	70.94	gold quality
right frontal lobe	UBERON:0002810	69.63	gold quality
body of pancreas	UBERON:0001150	69.49	gold quality
frontal cortex	UBERON:0001870	69.47	gold quality
transverse colon	UBERON:0001157	69.38	gold quality
right atrium auricular region	UBERON:0006631	68.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.