MIR6795

Summary

MIR6795 (microRNA 6795, HGNC:50031) is a microRNA gene on chromosome 19p13.12.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465476 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50031
Approved symbol	MIR6795
Name	microRNA 6795
Location	19p13.12
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6795
Ensembl gene	ENSG00000275711
Ensembl biotype	miRNA
Entrez	102465476
RNAcentral	URS000075DB8E — ncRNA, 68 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000620824

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000620824 — 1 exons

Exon	Start	End
ENSE00003721468	15179283	15179350

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 96.02.

Top tissues by expression

34 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	96.02	gold quality
intestine	UBERON:0000160	75.22	gold quality
stomach	UBERON:0000945	73.65	gold quality
kidney	UBERON:0002113	73.49	gold quality
gastrocnemius	UBERON:0001388	73.06	gold quality
body of stomach	UBERON:0001161	71.76	gold quality
heart left ventricle	UBERON:0002084	69.96	gold quality
omental fat pad	UBERON:0010414	69.77	gold quality
endometrium	UBERON:0001295	68.21	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.39	gold quality
tibial artery	UBERON:0007610	67.35	gold quality
tibial nerve	UBERON:0001323	67.12	gold quality
anterior cingulate cortex	UBERON:0009835	67.04	gold quality
adult mammalian kidney	UBERON:0000082	66.58	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.84	gold quality
ascending aorta	UBERON:0001496	65.74	gold quality
skin of abdomen	UBERON:0001416	65.68	gold quality
left ovary	UBERON:0002119	65.33	gold quality
skin of leg	UBERON:0001511	64.81	gold quality
esophagus mucosa	UBERON:0002469	64.36	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.28	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.08	gold quality
frontal cortex	UBERON:0001870	63.19	gold quality
hypothalamus	UBERON:0001898	63.12	gold quality
left coronary artery	UBERON:0001626	62.43	gold quality
prostate gland	UBERON:0002367	62.30	gold quality
vagina	UBERON:0000996	61.27	gold quality
right lobe of thyroid gland	UBERON:0001119	60.61	gold quality
right ovary	UBERON:0002118	60.56	gold quality
left lobe of thyroid gland	UBERON:0001120	60.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.