MIR6796

Summary

MIR6796 (microRNA 6796, HGNC:50186) is a microRNA gene on chromosome 19q13.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465477 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50186
Approved symbol	MIR6796
Name	microRNA 6796
Location	19q13.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6796
Ensembl gene	ENSG00000275652
Ensembl biotype	miRNA
Entrez	102465477
RNAcentral	URS000075AF04 — ncRNA, 62 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000617519

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000617519 — 1 exons

Exon	Start	End
ENSE00003748501	40369846	40369907

Expression profiles

Bgee: expression breadth broad, 82 present calls, max score 81.55.

Top tissues by expression

82 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	81.55	gold quality
calcaneal tendon	UBERON:0003701	79.68	gold quality
monocyte	CL:0000576	76.71	gold quality
blood	UBERON:0000178	76.29	gold quality
muscle of leg	UBERON:0001383	75.84	gold quality
liver	UBERON:0002107	75.41	gold quality
gastrocnemius	UBERON:0001388	74.11	gold quality
ectocervix	UBERON:0012249	71.47	gold quality
left adrenal gland cortex	UBERON:0035825	70.40	gold quality
gall bladder	UBERON:0002110	70.37	gold quality
fundus of stomach	UBERON:0001160	70.24	gold quality
left coronary artery	UBERON:0001626	70.15	gold quality
heart left ventricle	UBERON:0002084	69.99	gold quality
body of pancreas	UBERON:0001150	69.76	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.76	gold quality
stomach	UBERON:0000945	69.71	gold quality
kidney	UBERON:0002113	69.46	gold quality
adult mammalian kidney	UBERON:0000082	69.36	gold quality
heart	UBERON:0000948	69.34	gold quality
popliteal artery	UBERON:0002250	69.30	gold quality
tibial artery	UBERON:0007610	69.29	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.20	gold quality
anterior cingulate cortex	UBERON:0009835	69.07	gold quality
right frontal lobe	UBERON:0002810	69.00	gold quality
cerebral cortex	UBERON:0000956	68.88	gold quality
right atrium auricular region	UBERON:0006631	68.66	gold quality
body of stomach	UBERON:0001161	68.51	gold quality
upper lobe of left lung	UBERON:0008952	68.50	gold quality
endometrium	UBERON:0001295	68.41	gold quality
left uterine tube	UBERON:0001303	68.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• circSKA3 acts as a sponge of miR-6796-5p to be associated with outcomes of ischemic stroke by regulating matrix metalloproteinase 9 expression. (PMID:34725884)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.