MIR6798

Summary

MIR6798 (microRNA 6798, HGNC:50013) is a microRNA gene on chromosome 19q13.33.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102466738 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50013
Approved symbol	MIR6798
Name	microRNA 6798
Location	19q13.33
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6798
Ensembl gene	ENSG00000273898
Ensembl biotype	miRNA
Entrez	102466738
RNAcentral	URS000075C9C1 — ncRNA, 67 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000612887

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000612887 — 1 exons

Exon	Start	End
ENSE00003720596	49009906	49009972

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 81.64.

Top tissues by expression

41 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	81.64	gold quality
placenta	UBERON:0001987	76.15	gold quality
blood	UBERON:0000178	75.12	gold quality
gastrocnemius	UBERON:0001388	73.39	gold quality
heart left ventricle	UBERON:0002084	70.37	gold quality
body of stomach	UBERON:0001161	69.93	gold quality
body of uterus	UBERON:0009853	69.10	gold quality
skin of leg	UBERON:0001511	68.18	gold quality
transverse colon	UBERON:0001157	68.09	gold quality
substantia nigra	UBERON:0002038	67.82	gold quality
skin of abdomen	UBERON:0001416	66.80	gold quality
tibial artery	UBERON:0007610	66.80	gold quality
granulocyte	CL:0000094	66.79	gold quality
omental fat pad	UBERON:0010414	66.61	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.16	gold quality
putamen	UBERON:0001874	66.13	gold quality
right frontal lobe	UBERON:0002810	65.64	gold quality
adult mammalian kidney	UBERON:0000082	65.44	gold quality
caudate nucleus	UBERON:0001873	65.35	gold quality
left lobe of thyroid gland	UBERON:0001120	64.24	gold quality
thyroid gland	UBERON:0002046	64.09	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.52	gold quality
prostate gland	UBERON:0002367	62.92	gold quality
upper lobe of left lung	UBERON:0008952	62.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	62.80	gold quality
lung	UBERON:0002048	62.71	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.54	gold quality
right hemisphere of cerebellum	UBERON:0014890	62.11	gold quality
amygdala	UBERON:0001876	62.00	gold quality
minor salivary gland	UBERON:0001830	61.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.