MIR6799

Summary

MIR6799 (microRNA 6799, HGNC:50162) is a microRNA gene on chromosome 19q13.33.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465479 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50162
Approved symbol	MIR6799
Name	microRNA 6799
Location	19q13.33
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6799
Ensembl gene	ENSG00000276270
Ensembl biotype	miRNA
Entrez	102465479
RNAcentral	URS000075BAC2 — ncRNA, 69 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000620297

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000620297 — 1 exons

Exon	Start	End
ENSE00003735422	49791866	49791934

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 82.30.

Top tissues by expression

63 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	82.30	gold quality
monocyte	CL:0000576	80.87	gold quality
blood	UBERON:0000178	76.07	gold quality
gastrocnemius	UBERON:0001388	76.07	gold quality
right atrium auricular region	UBERON:0006631	73.25	gold quality
left coronary artery	UBERON:0001626	72.13	gold quality
heart left ventricle	UBERON:0002084	72.12	gold quality
adult mammalian kidney	UBERON:0000082	71.80	gold quality
stomach	UBERON:0000945	71.69	gold quality
right lobe of liver	UBERON:0001114	71.65	gold quality
left adrenal gland cortex	UBERON:0035825	70.69	gold quality
body of stomach	UBERON:0001161	70.15	gold quality
body of pancreas	UBERON:0001150	70.08	gold quality
substantia nigra	UBERON:0002038	67.99	gold quality
myometrium	UBERON:0001296	67.63	gold quality
left adrenal gland	UBERON:0001234	67.45	gold quality
endometrium	UBERON:0001295	67.20	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.82	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.81	gold quality
skin of leg	UBERON:0001511	66.71	gold quality
transverse colon	UBERON:0001157	66.53	gold quality
right adrenal gland	UBERON:0001233	66.29	gold quality
right ovary	UBERON:0002118	65.82	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.81	gold quality
adipose tissue	UBERON:0001013	65.67	gold quality
skin of abdomen	UBERON:0001416	65.39	gold quality
tibial artery	UBERON:0007610	65.20	gold quality
left uterine tube	UBERON:0001303	65.17	gold quality
minor salivary gland	UBERON:0001830	65.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.