MIR6800

Summary

MIR6800 (microRNA 6800, HGNC:50042) is a microRNA gene on chromosome 19q13.33.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465480 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50042
Approved symbol	MIR6800
Name	microRNA 6800
Location	19q13.33
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6800
Ensembl gene	ENSG00000284114
Ensembl biotype	miRNA
Entrez	102465480
RNAcentral	URS000075D6D6 — miRNA, 82 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000614963

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000614963 — 1 exons

Exon	Start	End
ENSE00003716814	49832018	49832099

Expression profiles

Bgee: expression breadth broad, 38 present calls, max score 71.39.

Top tissues by expression

38 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
gastrocnemius	UBERON:0001388	71.39	gold quality
blood	UBERON:0000178	70.78	gold quality
left adrenal gland cortex	UBERON:0035825	70.26	gold quality
heart left ventricle	UBERON:0002084	69.35	gold quality
body of stomach	UBERON:0001161	66.92	gold quality
tibial artery	UBERON:0007610	66.68	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.15	gold quality
caudate nucleus	UBERON:0001873	64.73	gold quality
body of pancreas	UBERON:0001150	64.72	gold quality
right atrium auricular region	UBERON:0006631	63.60	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.77	gold quality
ascending aorta	UBERON:0001496	60.88	gold quality
descending thoracic aorta	UBERON:0002345	60.84	gold quality
prostate gland	UBERON:0002367	60.79	gold quality
ectocervix	UBERON:0012249	60.57	gold quality
omental fat pad	UBERON:0010414	60.43	gold quality
hypothalamus	UBERON:0001898	60.11	gold quality
transverse colon	UBERON:0001157	59.07	gold quality
skin of leg	UBERON:0001511	58.60	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.50	gold quality
left adrenal gland	UBERON:0001234	57.73	gold quality
right frontal lobe	UBERON:0002810	57.47	gold quality
substantia nigra	UBERON:0002038	56.86	gold quality
muscle layer of sigmoid colon	UBERON:0035805	56.54	gold quality
Ammon’s horn	UBERON:0001954	56.35	gold quality
tibial nerve	UBERON:0001323	56.20	gold quality
esophagus mucosa	UBERON:0002469	54.42	gold quality
left lobe of thyroid gland	UBERON:0001120	53.50	gold quality
cerebellar hemisphere	UBERON:0002245	52.93	gold quality
thyroid gland	UBERON:0002046	52.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.