MIR6802

Summary

MIR6802 (microRNA 6802, HGNC:50154) is a microRNA gene on chromosome 19q13.42.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465481 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50154
Approved symbol	MIR6802
Name	microRNA 6802
Location	19q13.42
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-6802
Ensembl gene	ENSG00000278328
Ensembl biotype	miRNA
Entrez	102465481
RNAcentral	URS000075EE6E — ncRNA, 65 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000617379

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000617379 — 1 exons

Exon	Start	End
ENSE00003726756	55239912	55239976

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 86.48.

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
vermiform appendix	UBERON:0001154	86.48	gold quality
bone marrow	UBERON:0002371	80.33	gold quality
adrenal tissue	UBERON:0018303	76.89	gold quality
blood	UBERON:0000178	75.29	gold quality
muscle of leg	UBERON:0001383	74.54	gold quality
left adrenal gland cortex	UBERON:0035825	73.94	gold quality
gastrocnemius	UBERON:0001388	73.31	gold quality
right lobe of liver	UBERON:0001114	71.98	gold quality
liver	UBERON:0002107	71.57	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.27	gold quality
heart left ventricle	UBERON:0002084	71.19	gold quality
stomach	UBERON:0000945	71.11	gold quality
left uterine tube	UBERON:0001303	70.62	gold quality
apex of heart	UBERON:0002098	70.60	gold quality
body of stomach	UBERON:0001161	70.04	gold quality
heart	UBERON:0000948	69.62	gold quality
lymph node	UBERON:0000029	69.51	gold quality
tibial artery	UBERON:0007610	69.36	gold quality
body of pancreas	UBERON:0001150	69.17	gold quality
right atrium auricular region	UBERON:0006631	68.85	gold quality
left adrenal gland	UBERON:0001234	68.80	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.64	gold quality
adrenal gland	UBERON:0002369	67.39	gold quality
granulocyte	CL:0000094	67.25	gold quality
lower esophagus muscularis layer	UBERON:0035833	67.08	gold quality
skin of abdomen	UBERON:0001416	67.03	gold quality
left coronary artery	UBERON:0001626	66.93	gold quality
ascending aorta	UBERON:0001496	66.71	gold quality
amygdala	UBERON:0001876	66.66	gold quality
thoracic aorta	UBERON:0001515	66.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.