MIR7107

Summary

MIR7107 (microRNA 7107, HGNC:50006) is a microRNA gene on chromosome 12q24.31.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465665 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50006
Approved symbol	MIR7107
Name	microRNA 7107
Location	12q24.31
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7107
Ensembl gene	ENSG00000284402
Ensembl biotype	miRNA
Entrez	102465665
RNAcentral	URS000075CB30 — miRNA, 80 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000611489

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000611489 — 1 exons

Exon	Start	End
ENSE00003711551	121444273	121444352

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 80.33.

Top tissues by expression

99 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	80.33	gold quality
monocyte	CL:0000576	77.14	gold quality
leukocyte	CL:0000738	76.46	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	75.88	gold quality
placenta	UBERON:0001987	75.80	gold quality
blood	UBERON:0000178	75.60	gold quality
lymph node	UBERON:0000029	75.26	gold quality
right uterine tube	UBERON:0001302	74.56	gold quality
endometrium	UBERON:0001295	74.24	gold quality
muscle of leg	UBERON:0001383	74.12	gold quality
gastrocnemius	UBERON:0001388	73.49	gold quality
islet of Langerhans	UBERON:0000006	73.15	gold quality
left coronary artery	UBERON:0001626	71.31	gold quality
prefrontal cortex	UBERON:0000451	71.19	gold quality
esophagus mucosa	UBERON:0002469	70.78	gold quality
body of stomach	UBERON:0001161	70.74	gold quality
skin of leg	UBERON:0001511	70.48	gold quality
stomach	UBERON:0000945	70.43	gold quality
heart	UBERON:0000948	70.32	gold quality
fallopian tube	UBERON:0003889	70.29	gold quality
heart left ventricle	UBERON:0002084	70.00	gold quality
zone of skin	UBERON:0000014	69.92	gold quality
esophagus	UBERON:0001043	69.71	gold quality
body of pancreas	UBERON:0001150	69.71	gold quality
right atrium auricular region	UBERON:0006631	69.56	gold quality
ectocervix	UBERON:0012249	69.34	gold quality
minor salivary gland	UBERON:0001830	69.04	gold quality
skin of abdomen	UBERON:0001416	68.96	gold quality
left adrenal gland cortex	UBERON:0035825	68.91	gold quality
tibial artery	UBERON:0007610	68.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.