MIR7110

Summary

MIR7110 (microRNA 7110, HGNC:50024) is a microRNA gene on chromosome 3q21.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465667 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50024
Approved symbol	MIR7110
Name	microRNA 7110
Location	3q21.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7110
Ensembl gene	ENSG00000284421
Ensembl biotype	miRNA
Entrez	102465667
RNAcentral	URS000075DD92 — miRNA, 86 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000612638

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000612638 — 1 exons

Exon	Start	End
ENSE00003713951	123161794	123161879

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 81.72.

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	81.72	gold quality
prostate gland	UBERON:0002367	79.36	gold quality
muscle of leg	UBERON:0001383	75.30	gold quality
gastrocnemius	UBERON:0001388	72.75	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	69.31	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.70	gold quality
body of stomach	UBERON:0001161	65.29	gold quality
heart left ventricle	UBERON:0002084	65.02	gold quality
tibial artery	UBERON:0007610	63.81	gold quality
left coronary artery	UBERON:0001626	63.23	gold quality
vagina	UBERON:0000996	62.39	gold quality
lung	UBERON:0002048	62.35	gold quality
blood	UBERON:0000178	62.33	gold quality
body of pancreas	UBERON:0001150	62.33	gold quality
right atrium auricular region	UBERON:0006631	62.33	gold quality
left lobe of thyroid gland	UBERON:0001120	62.04	gold quality
skin of leg	UBERON:0001511	61.15	gold quality
left adrenal gland cortex	UBERON:0035825	59.94	gold quality
esophagus mucosa	UBERON:0002469	59.70	gold quality
minor salivary gland	UBERON:0001830	58.48	gold quality
left adrenal gland	UBERON:0001234	58.35	gold quality
hypothalamus	UBERON:0001898	57.10	gold quality
upper lobe of left lung	UBERON:0008952	56.30	gold quality
transverse colon	UBERON:0001157	55.56	gold quality
skin of abdomen	UBERON:0001416	54.87	gold quality
muscle layer of sigmoid colon	UBERON:0035805	54.76	gold quality
subcutaneous adipose tissue	UBERON:0002190	53.74	gold quality
left ovary	UBERON:0002119	51.84	gold quality
small intestine Peyer’s patch	UBERON:0003454	48.61	gold quality
omental fat pad	UBERON:0010414	48.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.