MIR7150

Summary

MIR7150 (microRNA 7150, HGNC:49982) is a microRNA gene on chromosome 9q33.3.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465688 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49982
Approved symbol	MIR7150
Name	microRNA 7150
Location	9q33.3
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7150
Ensembl gene	ENSG00000274932
Ensembl biotype	miRNA
Entrez	102465688
RNAcentral	URS000075DA11 — miRNA, 94 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000614393

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000614393 — 1 exons

Exon	Start	End
ENSE00003725307	123485529	123485622

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 82.05.

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	82.05	gold quality
calcaneal tendon	UBERON:0003701	81.60	gold quality
blood	UBERON:0000178	80.55	gold quality
adult mammalian kidney	UBERON:0000082	77.50	gold quality
heart left ventricle	UBERON:0002084	74.78	gold quality
liver	UBERON:0002107	72.57	gold quality
monocyte	CL:0000576	71.96	gold quality
heart	UBERON:0000948	70.66	gold quality
stomach	UBERON:0000945	70.17	gold quality
skin of leg	UBERON:0001511	68.89	gold quality
gastrocnemius	UBERON:0001388	68.75	gold quality
endometrium	UBERON:0001295	68.30	gold quality
body of pancreas	UBERON:0001150	68.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	68.00	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	67.83	gold quality
right lobe of liver	UBERON:0001114	67.73	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.63	gold quality
esophagus mucosa	UBERON:0002469	67.61	gold quality
ascending aorta	UBERON:0001496	67.53	gold quality
hypothalamus	UBERON:0001898	67.53	gold quality
tibial artery	UBERON:0007610	67.05	gold quality
intestine	UBERON:0000160	67.00	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.80	gold quality
lung	UBERON:0002048	66.33	gold quality
colon	UBERON:0001155	65.80	gold quality
omental fat pad	UBERON:0010414	65.70	gold quality
nucleus accumbens	UBERON:0001882	65.58	gold quality
corpus callosum	UBERON:0002336	65.43	gold quality
anterior cingulate cortex	UBERON:0009835	65.22	gold quality
myometrium	UBERON:0001296	65.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.