MIR7152

Summary

MIR7152 (microRNA 7152, HGNC:50257) is a microRNA gene on chromosome 10q22.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465689 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50257
Approved symbol	MIR7152
Name	microRNA 7152
Location	10q22.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7152
Ensembl gene	ENSG00000274824
Ensembl biotype	miRNA
Entrez	102465689
RNAcentral	URS000075B512 — ncRNA, 54 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000619512

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000619512 — 1 exons

Exon	Start	End
ENSE00003749678	71790747	71790800

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 99.10.

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.10	gold quality
left ovary	UBERON:0002119	95.45	gold quality
skeletal muscle tissue	UBERON:0001134	94.47	gold quality
ovary	UBERON:0000992	94.33	gold quality
right ovary	UBERON:0002118	93.05	gold quality
lower esophagus muscularis layer	UBERON:0035833	89.51	gold quality
lower esophagus	UBERON:0013473	89.50	gold quality
left uterine tube	UBERON:0001303	87.64	gold quality
right hemisphere of cerebellum	UBERON:0014890	86.64	gold quality
body of pancreas	UBERON:0001150	86.56	gold quality
pancreas	UBERON:0001264	86.46	gold quality
apex of heart	UBERON:0002098	85.65	gold quality
cerebellar hemisphere	UBERON:0002245	85.26	gold quality
granulocyte	CL:0000094	84.86	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	84.65	gold quality
myometrium	UBERON:0001296	84.03	gold quality
blood	UBERON:0000178	83.45	gold quality
esophagus	UBERON:0001043	82.97	gold quality
right lobe of liver	UBERON:0001114	82.71	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	82.40	gold quality
vermiform appendix	UBERON:0001154	82.23	gold quality
body of uterus	UBERON:0009853	82.00	gold quality
omental fat pad	UBERON:0010414	81.97	gold quality
monocyte	CL:0000576	81.91	gold quality
liver	UBERON:0002107	81.65	gold quality
fallopian tube	UBERON:0003889	81.61	gold quality
bone marrow	UBERON:0002371	81.08	gold quality
heart left ventricle	UBERON:0002084	80.87	gold quality
corpus callosum	UBERON:0002336	80.33	gold quality
lung	UBERON:0002048	80.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.