MIR7155

Summary

MIR7155 (microRNA 7155, HGNC:50005) is a microRNA gene on chromosome 11q13.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102466815 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50005
Approved symbol	MIR7155
Name	microRNA 7155
Location	11q13.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7155
Ensembl gene	ENSG00000278359
Ensembl biotype	miRNA
Entrez	102466815
RNAcentral	URS000075CEF4 — miRNA, 56 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000615925

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000615925 — 1 exons

Exon	Start	End
ENSE00003714778	64341849	64341904

Expression profiles

Bgee: expression breadth broad, 57 present calls, max score 78.15.

Top tissues by expression

57 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	78.15	gold quality
right lobe of liver	UBERON:0001114	76.07	gold quality
monocyte	CL:0000576	75.89	gold quality
adult mammalian kidney	UBERON:0000082	73.58	gold quality
skin of leg	UBERON:0001511	72.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.56	gold quality
body of pancreas	UBERON:0001150	72.53	gold quality
tibial artery	UBERON:0007610	72.15	gold quality
body of stomach	UBERON:0001161	71.81	gold quality
right atrium auricular region	UBERON:0006631	71.55	gold quality
right frontal lobe	UBERON:0002810	70.39	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.77	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.62	gold quality
lower esophagus muscularis layer	UBERON:0035833	69.38	gold quality
cerebellar hemisphere	UBERON:0002245	69.30	gold quality
skin of abdomen	UBERON:0001416	67.97	gold quality
descending thoracic aorta	UBERON:0002345	67.81	gold quality
ascending aorta	UBERON:0001496	67.72	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.49	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	67.23	gold quality
body of uterus	UBERON:0009853	67.15	gold quality
omental fat pad	UBERON:0010414	67.09	gold quality
esophagus mucosa	UBERON:0002469	66.45	gold quality
substantia nigra	UBERON:0002038	66.28	gold quality
putamen	UBERON:0001874	65.78	gold quality
myometrium	UBERON:0001296	65.77	gold quality
transverse colon	UBERON:0001157	65.76	gold quality
liver	UBERON:0002107	65.74	gold quality
left ovary	UBERON:0002119	65.73	gold quality
Ammon’s horn	UBERON:0001954	64.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.