MIR7156

Summary

MIR7156 (microRNA 7156, HGNC:50023) is a microRNA gene on chromosome 1p31.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102466995 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50023
Approved symbol	MIR7156
Name	microRNA 7156
Location	1p31.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7156
Ensembl gene	ENSG00000276081
Ensembl biotype	miRNA
Entrez	102466995
RNAcentral	URS000075C1D3 — miRNA, 60 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000620979

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000620979 — 1 exons

Exon	Start	End
ENSE00003732594	77060143	77060202

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 98.40.

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.40	gold quality
adrenal tissue	UBERON:0018303	79.25	gold quality
gastrocnemius	UBERON:0001388	76.72	gold quality
smooth muscle tissue	UBERON:0001135	76.51	gold quality
blood	UBERON:0000178	74.74	gold quality
gall bladder	UBERON:0002110	73.48	gold quality
left coronary artery	UBERON:0001626	72.68	gold quality
left adrenal gland cortex	UBERON:0035825	72.67	gold quality
islet of Langerhans	UBERON:0000006	72.37	gold quality
stomach	UBERON:0000945	71.63	gold quality
right adrenal gland cortex	UBERON:0035827	71.47	gold quality
endometrium	UBERON:0001295	71.33	gold quality
fundus of stomach	UBERON:0001160	70.84	gold quality
heart	UBERON:0000948	70.81	gold quality
tibial nerve	UBERON:0001323	70.58	gold quality
ascending aorta	UBERON:0001496	70.58	gold quality
right adrenal gland	UBERON:0001233	70.38	gold quality
thoracic aorta	UBERON:0001515	70.29	gold quality
body of pancreas	UBERON:0001150	70.04	gold quality
tibial artery	UBERON:0007610	69.92	gold quality
left adrenal gland	UBERON:0001234	69.87	gold quality
heart left ventricle	UBERON:0002084	69.71	gold quality
body of stomach	UBERON:0001161	69.30	gold quality
muscle layer of sigmoid colon	UBERON:0035805	69.12	gold quality
left ovary	UBERON:0002119	68.92	gold quality
right atrium auricular region	UBERON:0006631	68.82	gold quality
endocervix	UBERON:0000458	68.77	gold quality
hypothalamus	UBERON:0001898	68.63	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.63	gold quality
left uterine tube	UBERON:0001303	68.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• A novel miR-7156-3p-HOXD13 axis modulates glioma progression by regulating tumor cell stemness. (PMID:33162825)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.