MIR7162

Summary

MIR7162 (microRNA 7162, HGNC:50189) is a microRNA gene on chromosome 10p11.23.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102466227 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50189
Approved symbol	MIR7162
Name	microRNA 7162
Location	10p11.23
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7162
Ensembl gene	ENSG00000284277
Ensembl biotype	miRNA
Entrez	102466227
RNAcentral	URS000075D9DE — miRNA, 69 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000611134

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000611134 — 1 exons

Exon	Start	End
ENSE00003732859	30368597	30368665

Expression profiles

Bgee: expression breadth broad, 27 present calls, max score 72.90.

Top tissues by expression

27 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of stomach	UBERON:0001161	72.90	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.02	gold quality
ascending aorta	UBERON:0001496	68.46	gold quality
urinary bladder	UBERON:0001255	68.41	gold quality
endometrium	UBERON:0001295	68.40	gold quality
fallopian tube	UBERON:0003889	67.88	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.68	gold quality
esophagus mucosa	UBERON:0002469	66.48	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.93	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	64.84	gold quality
omental fat pad	UBERON:0010414	64.64	gold quality
right ovary	UBERON:0002118	63.29	gold quality
skin of abdomen	UBERON:0001416	62.70	gold quality
anterior cingulate cortex	UBERON:0009835	62.69	gold quality
skin of leg	UBERON:0001511	61.92	gold quality
vagina	UBERON:0000996	61.80	gold quality
right frontal lobe	UBERON:0002810	61.10	gold quality
myometrium	UBERON:0001296	60.97	gold quality
minor salivary gland	UBERON:0001830	57.98	gold quality
tibial nerve	UBERON:0001323	56.49	gold quality
ovary	UBERON:0000992	53.74	gold quality
tibial artery	UBERON:0007610	53.67	gold quality
left ovary	UBERON:0002119	52.63	gold quality
spleen	UBERON:0002106	49.13	gold quality
right testis	UBERON:0004534	48.61	gold quality
testis	UBERON:0000473	45.19	gold quality
left testis	UBERON:0004533	44.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.