MIR7844

Summary

MIR7844 (microRNA 7844, HGNC:50044) is a microRNA gene on chromosome 12q22.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465834 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50044
Approved symbol	MIR7844
Name	microRNA 7844
Location	12q22
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7844
Ensembl gene	ENSG00000283818
Ensembl biotype	miRNA
Entrez	102465834
RNAcentral	URS000075BC22 — miRNA, 122 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000616161

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000616161 — 1 exons

Exon	Start	End
ENSE00003754227	94571231	94571352

Expression profiles

Bgee: expression breadth broad, 49 present calls, max score 83.06.

Top tissues by expression

49 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.06	gold quality
blood	UBERON:0000178	82.04	gold quality
myometrium	UBERON:0001296	77.94	gold quality
skeletal muscle tissue	UBERON:0001134	75.37	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	74.35	gold quality
lung	UBERON:0002048	72.42	gold quality
skin of leg	UBERON:0001511	72.18	gold quality
muscle of leg	UBERON:0001383	70.49	gold quality
right lobe of thyroid gland	UBERON:0001119	70.09	gold quality
gastrocnemius	UBERON:0001388	69.71	gold quality
prostate gland	UBERON:0002367	69.45	gold quality
adult mammalian kidney	UBERON:0000082	68.03	gold quality
endometrium	UBERON:0001295	67.21	gold quality
tibial nerve	UBERON:0001323	66.65	gold quality
left coronary artery	UBERON:0001626	66.54	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.79	gold quality
adipose tissue	UBERON:0001013	65.60	gold quality
tibial artery	UBERON:0007610	65.10	gold quality
vagina	UBERON:0000996	64.31	gold quality
nucleus accumbens	UBERON:0001882	64.14	gold quality
stomach	UBERON:0000945	63.88	gold quality
right frontal lobe	UBERON:0002810	63.67	gold quality
body of stomach	UBERON:0001161	63.57	gold quality
liver	UBERON:0002107	63.11	gold quality
body of pancreas	UBERON:0001150	62.90	gold quality
lower esophagus muscularis layer	UBERON:0035833	62.47	gold quality
heart left ventricle	UBERON:0002084	62.46	gold quality
left lobe of thyroid gland	UBERON:0001120	61.27	gold quality
omental fat pad	UBERON:0010414	61.05	gold quality
small intestine Peyer’s patch	UBERON:0003454	60.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.