MIR7847

Summary

MIR7847 (microRNA 7847, HGNC:50153) is a microRNA gene on chromosome 11p15.5.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465993 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50153
Approved symbol	MIR7847
Name	microRNA 7847
Location	11p15.5
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7847
Ensembl gene	ENSG00000284594
Ensembl biotype	miRNA
Entrez	102465993
RNAcentral	URS00007E3EE0 — miRNA, 103 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000610912

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000610912 — 1 exons

Exon	Start	End
ENSE00003746147	1880045	1880147

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 84.34.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skin of abdomen	UBERON:0001416	84.34	gold quality
sural nerve	UBERON:0015488	84.10	gold quality
zone of skin	UBERON:0000014	83.61	gold quality
skin of leg	UBERON:0001511	83.14	gold quality
left adrenal gland cortex	UBERON:0035825	81.74	gold quality
right adrenal gland	UBERON:0001233	80.85	gold quality
bone marrow	UBERON:0002371	80.39	gold quality
left adrenal gland	UBERON:0001234	80.27	gold quality
adrenal gland	UBERON:0002369	79.95	gold quality
right adrenal gland cortex	UBERON:0035827	77.18	gold quality
blood	UBERON:0000178	77.12	gold quality
monocyte	CL:0000576	76.26	gold quality
spleen	UBERON:0002106	76.13	gold quality
muscle of leg	UBERON:0001383	75.87	gold quality
gastrocnemius	UBERON:0001388	75.08	gold quality
calcaneal tendon	UBERON:0003701	73.98	gold quality
right lobe of liver	UBERON:0001114	73.30	gold quality
endocervix	UBERON:0000458	72.89	gold quality
heart left ventricle	UBERON:0002084	72.07	gold quality
stomach	UBERON:0000945	71.98	gold quality
body of stomach	UBERON:0001161	71.76	gold quality
subcutaneous adipose tissue	UBERON:0002190	71.67	gold quality
body of pancreas	UBERON:0001150	71.30	gold quality
heart	UBERON:0000948	71.29	gold quality
adipose tissue	UBERON:0001013	71.24	gold quality
ectocervix	UBERON:0012249	71.05	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	70.90	gold quality
omental fat pad	UBERON:0010414	70.79	gold quality
esophagus mucosa	UBERON:0002469	70.74	gold quality
right atrium auricular region	UBERON:0006631	70.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• lncRNA IL-17RA-1 Attenuates LPS-Induced Sepsis via miR-7847-3p/PRKCG-Mediated MAPK Signaling Pathway. (PMID:36274974)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.