MIR7855

Summary

MIR7855 (microRNA 7855, HGNC:50244) is a microRNA gene on chromosome 14q23.3.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465841 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50244
Approved symbol	MIR7855
Name	microRNA 7855
Location	14q23.3
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-7855
Ensembl gene	ENSG00000284269
Ensembl biotype	miRNA
Entrez	102465841
RNAcentral	URS000075EB46 — ncRNA, 61 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000622027

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000622027 — 1 exons

Exon	Start	End
ENSE00003754811	64785626	64785686

Expression profiles

Bgee: expression breadth broad, 15 present calls, max score 81.04.

Top tissues by expression

15 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	81.04	gold quality
muscle of leg	UBERON:0001383	75.22	gold quality
blood	UBERON:0000178	74.96	gold quality
gastrocnemius	UBERON:0001388	73.48	gold quality
tibial artery	UBERON:0007610	71.29	gold quality
nucleus accumbens	UBERON:0001882	66.08	gold quality
cerebellar hemisphere	UBERON:0002245	65.67	gold quality
esophagus mucosa	UBERON:0002469	65.65	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.44	gold quality
anterior cingulate cortex	UBERON:0009835	64.42	gold quality
right frontal lobe	UBERON:0002810	63.50	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.09	gold quality
spleen	UBERON:0002106	61.55	gold quality
caudate nucleus	UBERON:0001873	61.24	gold quality
pituitary gland	UBERON:0000007	58.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.11

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• The AC006262.5-miR-7855-5p-BPY2C axis facilitates hepatocellular carcinoma proliferation and migration. (PMID:32956593)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.