MIR8062

Summary

MIR8062 (microRNA 8062, HGNC:49975) is a microRNA gene on chromosome 20p12.3.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 102465865 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49975
Approved symbol	MIR8062
Name	microRNA 8062
Location	20p12.3
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-8062
Ensembl gene	ENSG00000278159
Ensembl biotype	miRNA
Entrez	102465865
RNAcentral	URS000075ABA0 — miRNA, 85 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000621515

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000621515 — 1 exons

Exon	Start	End
ENSE00003732906	7371608	7371692

Expression profiles

Bgee: expression breadth tissue_specific, 7 present calls, max score 80.40.

Top tissues by expression

7 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
gastrocnemius	UBERON:0001388	80.40	gold quality
monocyte	CL:0000576	75.00	gold quality
tibial artery	UBERON:0007610	71.65	gold quality
left ovary	UBERON:0002119	61.61	gold quality
prostate gland	UBERON:0002367	60.09	gold quality
left testis	UBERON:0004533	42.26	gold quality
corpus callosum	UBERON:0002336	40.74	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.