MIS18A-AS1

Summary

MIS18A-AS1 (MIS18A antisense RNA 1, HGNC:40106) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40106
Approved symbol	MIS18A-AS1
Name	MIS18A antisense RNA 1
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227256
Ensembl biotype	lncRNA
Entrez	100874202
RNAcentral	URS00021231DA — lncRNA, 1795 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000453549, ENST00000783173, ENST00000783174

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453549 — 3 exons

Exon	Start	End
ENSE00001652395	32280593	32280988
ENSE00001727266	32277863	32278084
ENSE00001762978	32278381	32278531

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 88.47.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.47	gold quality
bone marrow cell	CL:0002092	72.41	gold quality
colonic epithelium	UBERON:0000397	69.63	silver quality
cortical plate	UBERON:0005343	67.00	gold quality
ventricular zone	UBERON:0003053	63.24	gold quality
bone marrow	UBERON:0002371	62.82	gold quality
ganglionic eminence	UBERON:0004023	62.77	gold quality
sural nerve	UBERON:0015488	62.04	silver quality
endometrium	UBERON:0001295	61.99	gold quality
lymph node	UBERON:0000029	59.73	gold quality
pituitary gland	UBERON:0000007	59.72	gold quality
right uterine tube	UBERON:0001302	59.44	gold quality
duodenum	UBERON:0002114	59.07	gold quality
skeletal muscle tissue	UBERON:0001134	59.03	gold quality
adenohypophysis	UBERON:0002196	58.42	gold quality
prefrontal cortex	UBERON:0000451	58.18	gold quality
primary visual cortex	UBERON:0002436	57.53	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.49	gold quality
islet of Langerhans	UBERON:0000006	57.07	gold quality
hypothalamus	UBERON:0001898	57.04	gold quality
tonsil	UBERON:0002372	56.45	gold quality
frontal cortex	UBERON:0001870	55.89	gold quality
superior frontal gyrus	UBERON:0002661	55.88	gold quality
metanephros cortex	UBERON:0010533	55.82	gold quality
Brodmann (1909) area 9	UBERON:0013540	55.64	gold quality
substantia nigra	UBERON:0002038	55.26	gold quality
left ovary	UBERON:0002119	54.95	gold quality
brain	UBERON:0000955	54.78	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.61	gold quality
cerebral cortex	UBERON:0000956	54.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.