MMADHC-DT

Summary

MMADHC-DT (MMADHC divergent transcript, HGNC:41087) is a long non-coding RNA gene on chromosome 2q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41087
Approved symbol	MMADHC-DT
Name	MMADHC divergent transcript
Location	2q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231969
Ensembl biotype	lncRNA
Entrez	101929231
RNAcentral	URS000075C364 — lncRNA, 873 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000449714, ENST00000655697, ENST00000657556, ENST00000660089, ENST00000665276, ENST00000687950, ENST00000689856, ENST00000702116, ENST00000790968, ENST00000790969, ENST00000790970, ENST00000790971, ENST00000790972, ENST00000790973, ENST00000790974, ENST00000790975, ENST00000790976, ENST00000790977, ENST00000790978, ENST00000790979, ENST00000790980, ENST00000790981, ENST00000790982, ENST00000790983, ENST00000790984, ENST00000790985, ENST00000790986, ENST00000790987, ENST00000790988

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449714 — 3 exons

Exon	Start	End
ENSE00001774550	149743718	149743759
ENSE00003936332	149587306	149587873
ENSE00004171750	149847909	149848236

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 86.29.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5583 / max 26.3821, expressed in 219 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
23022	0.3224	156
23021	0.1548	51
202437	0.0811	31

Top tissues by expression

135 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.29	gold quality
corpus callosum	UBERON:0002336	78.74	gold quality
liver	UBERON:0002107	74.80	gold quality
right lobe of liver	UBERON:0001114	73.93	gold quality
sural nerve	UBERON:0015488	72.58	gold quality
testis	UBERON:0000473	71.78	gold quality
bone marrow cell	CL:0002092	71.66	silver quality
left testis	UBERON:0004533	71.30	gold quality
spinal cord	UBERON:0002240	70.53	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.53	gold quality
quadriceps femoris	UBERON:0001377	70.37	gold quality
right testis	UBERON:0004534	70.32	gold quality
bone marrow	UBERON:0002371	68.92	gold quality
substantia nigra	UBERON:0002038	67.15	gold quality
thymus	UBERON:0002370	66.96	silver quality
calcaneal tendon	UBERON:0003701	66.66	gold quality
cortical plate	UBERON:0005343	66.57	gold quality
ganglionic eminence	UBERON:0004023	66.17	gold quality
stromal cell of endometrium	CL:0002255	65.58	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.11	gold quality
tibial nerve	UBERON:0001323	64.79	gold quality
skeletal muscle tissue	UBERON:0001134	64.62	gold quality
duodenum	UBERON:0002114	64.53	gold quality
ventricular zone	UBERON:0003053	64.41	gold quality
muscle of leg	UBERON:0001383	64.18	gold quality
prefrontal cortex	UBERON:0000451	63.94	gold quality
gastrocnemius	UBERON:0001388	63.92	gold quality
gall bladder	UBERON:0002110	63.77	gold quality
temporal lobe	UBERON:0001871	63.45	gold quality
amygdala	UBERON:0001876	63.35	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	49.64
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.