MMEL1-AS1

Summary

MMEL1-AS1 (MMEL1 antisense RNA 1, HGNC:40695) is a long non-coding RNA gene on chromosome 1p36.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40695
Approved symbol	MMEL1-AS1
Name	MMEL1 antisense RNA 1
Location	1p36.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237058
Ensembl biotype	lncRNA
Entrez	105378597
RNAcentral	URS00026A278E — lncRNA, 587 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000427302, ENST00000723522, ENST00000723523, ENST00000723524, ENST00000723525, ENST00000723526, ENST00000723527, ENST00000723528, ENST00000723529, ENST00000723530, ENST00000723531, ENST00000723532

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427302 — 3 exons

Exon	Start	End
ENSE00004045271	2628721	2628903
ENSE00004045274	2636356	2636623
ENSE00004045275	2632502	2632675

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 87.08.

Top tissues by expression

97 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.08	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.92	gold quality
right testis	UBERON:0004534	78.13	gold quality
left testis	UBERON:0004533	78.00	gold quality
testis	UBERON:0000473	77.34	gold quality
ventricular zone	UBERON:0003053	70.11	gold quality
hypothalamus	UBERON:0001898	68.24	gold quality
liver	UBERON:0002107	66.83	silver quality
cortical plate	UBERON:0005343	66.25	gold quality
substantia nigra	UBERON:0002038	64.91	gold quality
cortex of kidney	UBERON:0001225	61.67	gold quality
monocyte	CL:0000576	59.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.38	gold quality
kidney	UBERON:0002113	58.86	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	58.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.33	gold quality
metanephros cortex	UBERON:0010533	57.89	gold quality
nucleus accumbens	UBERON:0001882	57.41	gold quality
adult mammalian kidney	UBERON:0000082	57.18	gold quality
multicellular organism	UBERON:0000468	56.26	gold quality
bone marrow	UBERON:0002371	55.92	gold quality
placenta	UBERON:0001987	55.87	gold quality
islet of Langerhans	UBERON:0000006	55.41	gold quality
vermiform appendix	UBERON:0001154	55.14	gold quality
brain	UBERON:0000955	54.92	gold quality
prefrontal cortex	UBERON:0000451	54.47	gold quality
Ammon’s horn	UBERON:0001954	54.23	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.04	gold quality
myometrium	UBERON:0001296	53.46	gold quality
blood	UBERON:0000178	53.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.