MMP2-AS1

Summary

MMP2-AS1 (MMP2 antisense RNA 1, HGNC:53142) is a long non-coding RNA gene on chromosome 16q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53142
Approved symbol	MMP2-AS1
Name	MMP2 antisense RNA 1
Location	16q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000569037
Ensembl gene	ENSG00000260135
Ensembl biotype	lncRNA
Entrez	107984884
RNAcentral	URS0000BC4636 — lncRNA, 800 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000565307, ENST00000569037, ENST00000620495, ENST00000664911, ENST00000789013, ENST00000789014, ENST00000789015, ENST00000789016, ENST00000789017

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000565307 — 3 exons

Exon	Start	End
ENSE00002590968	55444113	55444221
ENSE00002595101	55444622	55444759
ENSE00002597043	55429135	55429480

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 86.49.

FANTOM5 (CAGE): breadth broad, TPM avg 4.7244 / max 577.8920, expressed in 204 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
157443	2.6300	164
157442	1.6062	149
157437	0.3416	77
157441	0.0770	29
157436	0.0696	32

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.49	gold quality
right lung	UBERON:0002167	81.31	gold quality
upper lobe of left lung	UBERON:0008952	76.97	gold quality
spleen	UBERON:0002106	74.82	gold quality
lung	UBERON:0002048	74.63	gold quality
granulocyte	CL:0000094	74.61	gold quality
tonsil	UBERON:0002372	73.76	gold quality
lymph node	UBERON:0000029	71.66	gold quality
bone marrow cell	CL:0002092	70.41	silver quality
rectum	UBERON:0001052	69.80	gold quality
vermiform appendix	UBERON:0001154	68.44	gold quality
colonic epithelium	UBERON:0000397	65.82	silver quality
gall bladder	UBERON:0002110	64.23	gold quality
mucosa of transverse colon	UBERON:0004991	63.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.31	gold quality
leukocyte	CL:0000738	62.87	gold quality
monocyte	CL:0000576	62.23	gold quality
placenta	UBERON:0001987	61.57	gold quality
blood	UBERON:0000178	61.17	gold quality
metanephros cortex	UBERON:0010533	61.03	gold quality
bone marrow	UBERON:0002371	60.63	gold quality
subcutaneous adipose tissue	UBERON:0002190	60.36	gold quality
right coronary artery	UBERON:0001625	60.04	gold quality
ventricular zone	UBERON:0003053	59.41	gold quality
liver	UBERON:0002107	59.21	gold quality
cortex of kidney	UBERON:0001225	59.08	gold quality
skeletal muscle tissue	UBERON:0001134	58.99	silver quality
small intestine	UBERON:0002108	58.35	gold quality
small intestine Peyer’s patch	UBERON:0003454	58.15	gold quality
mucosa of stomach	UBERON:0001199	57.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.