MMP25-AS1

Summary

MMP25-AS1 (MMP25 antisense RNA 1, HGNC:51372) is a long non-coding RNA gene on chromosome 16p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51372
Approved symbol	MMP25-AS1
Name	MMP25 antisense RNA 1
Location	16p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261971
Ensembl biotype	lncRNA
Entrez	100507419
RNAcentral	URS000075AB0F — lncRNA, 2349 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000570949, ENST00000572222, ENST00000572427, ENST00000572574, ENST00000572930, ENST00000573130, ENST00000573878, ENST00000573953, ENST00000576250, ENST00000649784, ENST00000722316, ENST00000722317, ENST00000722318, ENST00000722319, ENST00000722320, ENST00000722321

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000570949 — 3 exons

Exon	Start	End
ENSE00002648655	3055736	3055945
ENSE00002666657	3054916	3055032
ENSE00002672322	3057050	3057213

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 92.18.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.3608 / max 96.6072, expressed in 1478 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
155998	4.3608	1478

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	92.18	gold quality
spleen	UBERON:0002106	90.59	gold quality
right uterine tube	UBERON:0001302	88.58	gold quality
blood	UBERON:0000178	87.88	gold quality
vermiform appendix	UBERON:0001154	87.69	gold quality
right lobe of thyroid gland	UBERON:0001119	85.81	gold quality
right hemisphere of cerebellum	UBERON:0014890	85.72	gold quality
left lobe of thyroid gland	UBERON:0001120	85.58	gold quality
body of pancreas	UBERON:0001150	85.44	gold quality
bone marrow cell	CL:0002092	85.14	gold quality
right lobe of liver	UBERON:0001114	84.68	gold quality
cerebellar hemisphere	UBERON:0002245	84.58	gold quality
cerebellar cortex	UBERON:0002129	84.50	gold quality
small intestine Peyer’s patch	UBERON:0003454	83.90	gold quality
thyroid gland	UBERON:0002046	83.87	gold quality
right testis	UBERON:0004534	83.82	gold quality
minor salivary gland	UBERON:0001830	83.78	gold quality
endocervix	UBERON:0000458	83.71	gold quality
metanephros cortex	UBERON:0010533	83.35	gold quality
ileal mucosa	UBERON:0000331	83.33	silver quality
caecum	UBERON:0001153	82.99	gold quality
left uterine tube	UBERON:0001303	82.91	gold quality
left testis	UBERON:0004533	82.88	gold quality
cerebellum	UBERON:0002037	82.67	gold quality
sural nerve	UBERON:0015488	82.54	gold quality
cardiac muscle of right atrium	UBERON:0003379	82.23	gold quality
apex of heart	UBERON:0002098	82.12	gold quality
left ventricle myocardium	UBERON:0006566	82.10	gold quality
upper lobe of left lung	UBERON:0008952	81.89	gold quality
adenohypophysis	UBERON:0002196	81.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.