MPPED2-AS1

Summary

MPPED2-AS1 (MPPED2 antisense RNA 1, HGNC:53909) is a long non-coding RNA gene on chromosome 11p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53909
Approved symbol	MPPED2-AS1
Name	MPPED2 antisense RNA 1
Location	11p14.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP5-1024C24.1
Ensembl gene	ENSG00000254489
Ensembl biotype	lncRNA
Entrez	105376609
RNAcentral	URS00026A1E20 — lncRNA, 3341 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000525871, ENST00000531002, ENST00000691848, ENST00000692592, ENST00000839576, ENST00000839577, ENST00000839578, ENST00000839579, ENST00000839580, ENST00000839581, ENST00000839582, ENST00000839583, ENST00000839584, ENST00000839585, ENST00000839586

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525871 — 2 exons

Exon	Start	End
ENSE00003984017	30584593	30584967
ENSE00004261976	30583963	30584233

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 92.94.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0570 / max 5.5055, expressed in 28 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
206236	0.0570	28

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	92.94	silver quality
ventricular zone	UBERON:0003053	79.18	gold quality
cerebellar vermis	UBERON:0004720	78.28	gold quality
right uterine tube	UBERON:0001302	77.57	gold quality
cortical plate	UBERON:0005343	75.23	gold quality
ganglionic eminence	UBERON:0004023	75.09	gold quality
left lobe of thyroid gland	UBERON:0001120	74.36	gold quality
thyroid gland	UBERON:0002046	74.27	gold quality
right lobe of thyroid gland	UBERON:0001119	73.76	gold quality
prostate gland	UBERON:0002367	71.18	gold quality
descending thoracic aorta	UBERON:0002345	69.95	gold quality
ascending aorta	UBERON:0001496	69.87	gold quality
thoracic aorta	UBERON:0001515	69.81	gold quality
sural nerve	UBERON:0015488	69.59	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
adult mammalian kidney	UBERON:0000082	68.73	gold quality
kidney	UBERON:0002113	67.80	gold quality
endocervix	UBERON:0000458	66.42	gold quality
myometrium	UBERON:0001296	65.99	gold quality
pituitary gland	UBERON:0000007	64.93	gold quality
cortex of kidney	UBERON:0001225	64.86	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.41	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	64.17	gold quality
body of uterus	UBERON:0009853	63.72	gold quality
adenohypophysis	UBERON:0002196	63.68	gold quality
smooth muscle tissue	UBERON:0001135	63.58	gold quality
tonsil	UBERON:0002372	63.03	gold quality
skeletal muscle tissue	UBERON:0001134	62.56	gold quality
prefrontal cortex	UBERON:0000451	62.30	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.