MRGPRF-AS1

Summary

MRGPRF-AS1 (MRGPRF antisense RNA 1, HGNC:51140) is a long non-coding RNA gene on chromosome 11q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51140
Approved symbol	MRGPRF-AS1
Name	MRGPRF antisense RNA 1
Location	11q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256508
Ensembl biotype	lncRNA
Entrez	101928200
RNAcentral	URS000075D8FB — lncRNA, 1597 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000538407, ENST00000569428, ENST00000569432, ENST00000842287, ENST00000842288, ENST00000842289, ENST00000842290, ENST00000842291, ENST00000842292, ENST00000842293, ENST00000842294, ENST00000842295, ENST00000842296, ENST00000842297, ENST00000842298, ENST00000842299, ENST00000842300, ENST00000842301, ENST00000842302

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000538407 — 6 exons

Exon	Start	End
ENSE00002251721	69012431	69012548
ENSE00002262127	69013791	69013904
ENSE00002276707	69017636	69018447
ENSE00002281414	69014131	69014316
ENSE00002321468	69014441	69014591
ENSE00002321665	69015611	69015719

Expression profiles

Bgee: expression breadth ubiquitous, 146 present calls, max score 97.78.

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.78	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.67	gold quality
body of uterus	UBERON:0009853	78.15	gold quality
mucosa of stomach	UBERON:0001199	77.03	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	76.94	gold quality
muscle layer of sigmoid colon	UBERON:0035805	76.77	gold quality
tibial artery	UBERON:0007610	75.21	gold quality
popliteal artery	UBERON:0002250	75.19	gold quality
lower esophagus muscularis layer	UBERON:0035833	75.02	gold quality
lower esophagus	UBERON:0013473	74.98	gold quality
aorta	UBERON:0000947	74.52	gold quality
descending thoracic aorta	UBERON:0002345	74.44	gold quality
left uterine tube	UBERON:0001303	74.22	gold quality
thoracic aorta	UBERON:0001515	74.06	gold quality
ascending aorta	UBERON:0001496	74.03	gold quality
sural nerve	UBERON:0015488	73.35	gold quality
endocervix	UBERON:0000458	72.50	gold quality
ectocervix	UBERON:0012249	72.22	gold quality
right ovary	UBERON:0002118	71.86	gold quality
left ovary	UBERON:0002119	71.30	gold quality
left coronary artery	UBERON:0001626	70.67	gold quality
right coronary artery	UBERON:0001625	70.24	gold quality
coronary artery	UBERON:0001621	69.93	gold quality
smooth muscle tissue	UBERON:0001135	69.30	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.03	gold quality
uterine cervix	UBERON:0000002	68.95	gold quality
cerebellar hemisphere	UBERON:0002245	68.49	gold quality
stromal cell of endometrium	CL:0002255	68.43	gold quality
cerebellar cortex	UBERON:0002129	68.21	gold quality
ovary	UBERON:0000992	66.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.