MRGPRG-AS1

Summary

MRGPRG-AS1 (MRGPRG antisense RNA 1, HGNC:26691) is a long non-coding RNA gene on chromosome 11p15.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26691
Approved symbol	MRGPRG-AS1
Name	MRGPRG antisense RNA 1
Location	11p15.4
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ36102, HSD-40
Ensembl gene	ENSG00000236301
Ensembl biotype	lncRNA
Entrez	283303
RNAcentral	URS000020E505 — lncRNA, 1790 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000420873, ENST00000434798, ENST00000531711, ENST00000820167, ENST00000820168, ENST00000820169, ENST00000820170, ENST00000820171

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420873 — 3 exons

Exon	Start	End
ENSE00001699592	3219700	3219788
ENSE00002193883	3221570	3223126
ENSE00002200372	3218388	3218559

Expression profiles

Bgee: expression breadth broad, 25 present calls, max score 99.61.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0111 / max 11.2771, expressed in 4 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
112727	0.0086	4
112726	0.0025	2

Top tissues by expression

162 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	99.61	gold quality
left testis	UBERON:0004533	71.88	gold quality
right testis	UBERON:0004534	70.79	gold quality
testis	UBERON:0000473	69.17	gold quality
upper leg skin	UBERON:0004262	64.95	silver quality
myocardium	UBERON:0002349	64.09	gold quality
endothelial cell	CL:0000115	59.45	gold quality
bone marrow	UBERON:0002371	59.00	gold quality
trabecular bone tissue	UBERON:0002483	57.83	gold quality
cerebellar hemisphere	UBERON:0002245	57.52	gold quality
cortical plate	UBERON:0005343	56.42	silver quality
cerebellar vermis	UBERON:0004720	56.01	gold quality
parotid gland	UBERON:0001831	55.37	gold quality
cartilage tissue	UBERON:0002418	55.29	gold quality
tibia	UBERON:0000979	54.45	gold quality
blood	UBERON:0000178	54.37	gold quality
vena cava	UBERON:0004087	53.98	gold quality
gingival epithelium	UBERON:0001949	53.90	gold quality
islet of Langerhans	UBERON:0000006	53.80	gold quality
skin of hip	UBERON:0001554	53.08	silver quality
saliva-secreting gland	UBERON:0001044	51.42	gold quality
esophagus squamous epithelium	UBERON:0006920	51.23	gold quality
biceps brachii	UBERON:0001507	50.60	gold quality
buccal mucosa cell	CL:0002336	50.51	gold quality
gingiva	UBERON:0001828	49.84	gold quality
cerebellum	UBERON:0002037	49.75	gold quality
skin of leg	UBERON:0001511	49.35	gold quality
medial globus pallidus	UBERON:0002477	49.25	gold quality
gastrocnemius	UBERON:0001388	48.62	gold quality
pharyngeal mucosa	UBERON:0000355	48.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.