MRPS35-DT

Summary

MRPS35-DT (MRPS35 divergent transcript, HGNC:55490) is a long non-coding RNA gene on chromosome 12p11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55490
Approved symbol	MRPS35-DT
Name	MRPS35 divergent transcript
Location	12p11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256377
Ensembl biotype	lncRNA
Entrez	107984461
RNAcentral	URS000018EE18 — lncRNA, 1110 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000536317, ENST00000536922, ENST00000542660, ENST00000656583, ENST00000740393, ENST00000740394, ENST00000740395, ENST00000740396, ENST00000740397

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000536317 — 4 exons

Exon	Start	End
ENSE00002236976	27704738	27704924
ENSE00002249136	27703461	27703620
ENSE00002258035	27696388	27696978
ENSE00002304708	27710599	27710770

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 92.54.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.54	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.84	gold quality
bone marrow cell	CL:0002092	73.70	silver quality
right testis	UBERON:0004534	72.60	gold quality
testis	UBERON:0000473	72.54	gold quality
left testis	UBERON:0004533	72.46	gold quality
stromal cell of endometrium	CL:0002255	72.12	gold quality
colonic epithelium	UBERON:0000397	70.81	gold quality
tonsil	UBERON:0002372	65.78	gold quality
calcaneal tendon	UBERON:0003701	63.91	gold quality
ventricular zone	UBERON:0003053	62.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.73	gold quality
ganglionic eminence	UBERON:0004023	62.18	gold quality
heart left ventricle	UBERON:0002084	62.11	gold quality
cortical plate	UBERON:0005343	61.82	gold quality
right coronary artery	UBERON:0001625	61.78	gold quality
mucosa of transverse colon	UBERON:0004991	61.22	gold quality
descending thoracic aorta	UBERON:0002345	61.21	gold quality
skeletal muscle tissue	UBERON:0001134	60.62	gold quality
endometrium	UBERON:0001295	60.40	gold quality
liver	UBERON:0002107	60.21	gold quality
apex of heart	UBERON:0002098	59.94	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.81	gold quality
heart	UBERON:0000948	59.06	gold quality
thoracic aorta	UBERON:0001515	58.97	gold quality
ascending aorta	UBERON:0001496	58.74	gold quality
islet of Langerhans	UBERON:0000006	58.60	gold quality
right lobe of liver	UBERON:0001114	58.58	gold quality
prefrontal cortex	UBERON:0000451	58.43	gold quality
duodenum	UBERON:0002114	58.40	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	2906.17
E-ANND-3	no	2.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.