MT-TP

Summary

MT-TP (mitochondrially encoded tRNA-Pro (CCN), HGNC:7494) is a mitochondrial tRNA gene on chromosome mitochondria.

At a glance

• Gene type: non-coding (Mt_tRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:7494
Approved symbol	MT-TP
Name	mitochondrially encoded tRNA-Pro (CCN)
Location	mitochondria
Locus type	RNA, transfer
Status	Approved
Aliases	trnP
Ensembl gene	ENSG00000210196
Ensembl biotype	Mt_tRNA
OMIM	590075
Entrez	4571
RNAcentral	URS000002176F — tRNA, 68 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 Mt_tRNA

ENST00000387461

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000387461 — 1 exons

Exon	Start	End
ENSE00001544473	15956	16023

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 99.98.

FANTOM5 (CAGE): breadth broad, TPM avg 3.0843 / max 1031.2089, expressed in 645 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
195302	1.8048	260
195303	1.2795	441

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
rectum	UBERON:0001052	99.98	gold quality
smooth muscle tissue	UBERON:0001135	99.97	gold quality
mucosa of stomach	UBERON:0001199	99.97	gold quality
right uterine tube	UBERON:0001302	99.96	gold quality
caudate nucleus	UBERON:0001873	99.96	gold quality
putamen	UBERON:0001874	99.96	gold quality
amygdala	UBERON:0001876	99.96	gold quality
nucleus accumbens	UBERON:0001882	99.96	gold quality
hypothalamus	UBERON:0001898	99.96	gold quality
right hemisphere of cerebellum	UBERON:0014890	99.96	gold quality
skeletal muscle tissue	UBERON:0001134	99.95	gold quality
fundus of stomach	UBERON:0001160	99.95	gold quality
frontal cortex	UBERON:0001870	99.95	gold quality
Ammon’s horn	UBERON:0001954	99.95	gold quality
substantia nigra	UBERON:0002038	99.95	gold quality
apex of heart	UBERON:0002098	99.95	gold quality
cerebellar hemisphere	UBERON:0002245	99.95	gold quality
right frontal lobe	UBERON:0002810	99.95	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	99.95	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	99.95	gold quality
granulocyte	CL:0000094	99.94	gold quality
cerebral cortex	UBERON:0000956	99.94	gold quality
endometrium	UBERON:0001295	99.94	gold quality
heart left ventricle	UBERON:0002084	99.94	gold quality
right testis	UBERON:0004534	99.94	gold quality
right atrium auricular region	UBERON:0006631	99.94	gold quality
Brodmann (1909) area 9	UBERON:0013540	99.94	gold quality
adrenal tissue	UBERON:0018303	99.94	gold quality
adult mammalian kidney	UBERON:0000082	99.93	gold quality
heart	UBERON:0000948	99.93	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-30	yes	489.37
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.