MT-TY
geneOn this page
Also known as trnY
Summary
MT-TY (mitochondrially encoded tRNA-Tyr (UAU/C), HGNC:7502) is a mitochondrial tRNA gene on chromosome mitochondria.
Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation.
Source: NCBI Gene 4579 — RefSeq curated summary.
At a glance
- Gene type: non-coding (Mt_tRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:7502 |
| Approved symbol | MT-TY |
| Name | mitochondrially encoded tRNA-Tyr (UAU/C) |
| Location | mitochondria |
| Locus type | RNA, transfer |
| Status | Approved |
| Aliases | trnY |
| Ensembl gene | ENSG00000210144 |
| Ensembl biotype | Mt_tRNA |
| OMIM | 590100 |
| Entrez | 4579 |
| RNAcentral | URS00000F3F5E — tRNA, 66 nt, 3 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 Mt_tRNA
ENST00000387409
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000387409 — 1 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001544488 | 5826 | 5891 |
Expression profiles
Bgee: expression breadth ubiquitous, 118 present calls, max score 99.95.
Top tissues by expression
118 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| skeletal muscle tissue | UBERON:0001134 | 99.95 | gold quality |
| duodenum | UBERON:0002114 | 99.94 | gold quality |
| adrenal tissue | UBERON:0018303 | 99.93 | gold quality |
| apex of heart | UBERON:0002098 | 99.92 | gold quality |
| vermiform appendix | UBERON:0001154 | 99.91 | gold quality |
| right uterine tube | UBERON:0001302 | 99.91 | gold quality |
| rectum | UBERON:0001052 | 99.88 | gold quality |
| amygdala | UBERON:0001876 | 99.85 | gold quality |
| mucosa of stomach | UBERON:0001199 | 99.84 | gold quality |
| fundus of stomach | UBERON:0001160 | 99.83 | gold quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 99.81 | gold quality |
| prefrontal cortex | UBERON:0000451 | 99.79 | gold quality |
| sural nerve | UBERON:0015488 | 99.79 | gold quality |
| stomach | UBERON:0000945 | 99.78 | gold quality |
| body of stomach | UBERON:0001161 | 99.77 | gold quality |
| right coronary artery | UBERON:0001625 | 99.72 | gold quality |
| hypothalamus | UBERON:0001898 | 99.71 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 99.70 | gold quality |
| right adrenal gland | UBERON:0001233 | 99.70 | gold quality |
| Ammon’s horn | UBERON:0001954 | 99.70 | gold quality |
| right adrenal gland cortex | UBERON:0035827 | 99.70 | gold quality |
| transverse colon | UBERON:0001157 | 99.68 | gold quality |
| skin of leg | UBERON:0001511 | 99.67 | gold quality |
| nucleus accumbens | UBERON:0001882 | 99.66 | gold quality |
| heart left ventricle | UBERON:0002084 | 99.63 | gold quality |
| zone of skin | UBERON:0000014 | 99.62 | gold quality |
| left uterine tube | UBERON:0001303 | 99.62 | gold quality |
| gastrocnemius | UBERON:0001388 | 99.62 | gold quality |
| caudate nucleus | UBERON:0001873 | 99.62 | gold quality |
| granulocyte | CL:0000094 | 99.58 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 14.02 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): Kearns-Sayre syndrome, MELAS syndrome, progressive external ophthalmoplegia