MTOR-AS1

Summary

MTOR-AS1 (MTOR antisense RNA 1, HGNC:40242) is a long non-coding RNA gene on chromosome 1p36.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40242
Approved symbol	MTOR-AS1
Name	MTOR antisense RNA 1
Location	1p36.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225602
Ensembl biotype	lncRNA
Entrez	100873935
RNAcentral	URS000075B5BB — lncRNA, 706 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000420480, ENST00000445982

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420480 — 4 exons

Exon	Start	End
ENSE00001605829	11149270	11149537
ENSE00001720984	11145153	11145279
ENSE00001736483	11144667	11144886
ENSE00001798340	11144424	11144481

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 85.19.

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.19	gold quality
sural nerve	UBERON:0015488	78.35	silver quality
bone marrow cell	CL:0002092	73.09	gold quality
tonsil	UBERON:0002372	67.66	gold quality
calcaneal tendon	UBERON:0003701	67.49	gold quality
ventricular zone	UBERON:0003053	65.68	gold quality
skeletal muscle tissue	UBERON:0001134	64.74	gold quality
ganglionic eminence	UBERON:0004023	62.57	gold quality
bone marrow	UBERON:0002371	62.36	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.17	gold quality
cortical plate	UBERON:0005343	59.78	gold quality
liver	UBERON:0002107	57.36	gold quality
uterine cervix	UBERON:0000002	57.02	gold quality
corpus callosum	UBERON:0002336	54.96	gold quality
stromal cell of endometrium	CL:0002255	54.42	silver quality
blood	UBERON:0000178	54.32	gold quality
leukocyte	CL:0000738	52.90	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	52.03	gold quality
monocyte	CL:0000576	51.78	silver quality
adrenal tissue	UBERON:0018303	51.60	gold quality
ectocervix	UBERON:0012249	51.53	gold quality
muscle of leg	UBERON:0001383	51.45	gold quality
cortex of kidney	UBERON:0001225	51.36	gold quality
urinary bladder	UBERON:0001255	50.39	gold quality
islet of Langerhans	UBERON:0000006	50.18	gold quality
lower esophagus mucosa	UBERON:0035834	49.83	gold quality
prefrontal cortex	UBERON:0000451	49.57	gold quality
gastrocnemius	UBERON:0001388	49.54	gold quality
kidney	UBERON:0002113	48.35	gold quality
right lobe of thyroid gland	UBERON:0001119	47.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.