MTTP-AS1

Summary

MTTP-AS1 (MTTP antisense RNA 1, HGNC:54189) is a long non-coding RNA gene on chromosome 4q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54189
Approved symbol	MTTP-AS1
Name	MTTP antisense RNA 1
Location	4q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248676
Ensembl biotype	lncRNA
Entrez	144093402

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000508578, ENST00000807449

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508578 — 4 exons

Exon	Start	End
ENSE00002067941	99595494	99595641
ENSE00002071462	99620887	99620982
ENSE00004201527	99594524	99594881
ENSE00004201528	99625882	99626001

Expression profiles

Bgee: expression breadth broad, 94 present calls, max score 92.90.

Top tissues by expression

94 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.90	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.96	gold quality
right lobe of liver	UBERON:0001114	81.44	gold quality
liver	UBERON:0002107	78.53	gold quality
duodenum	UBERON:0002114	78.07	gold quality
skeletal muscle tissue	UBERON:0001134	72.12	gold quality
small intestine	UBERON:0002108	72.06	gold quality
ventricular zone	UBERON:0003053	71.38	gold quality
small intestine Peyer’s patch	UBERON:0003454	71.12	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.28	gold quality
intestine	UBERON:0000160	63.53	gold quality
prefrontal cortex	UBERON:0000451	60.52	gold quality
calcaneal tendon	UBERON:0003701	58.75	gold quality
adult mammalian kidney	UBERON:0000082	56.88	gold quality
kidney	UBERON:0002113	56.88	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.33	gold quality
muscle of leg	UBERON:0001383	56.26	gold quality
gastrocnemius	UBERON:0001388	55.38	gold quality
monocyte	CL:0000576	55.37	gold quality
right atrium auricular region	UBERON:0006631	54.65	gold quality
left coronary artery	UBERON:0001626	54.34	gold quality
endometrium	UBERON:0001295	54.21	gold quality
islet of Langerhans	UBERON:0000006	53.94	gold quality
heart	UBERON:0000948	53.92	gold quality
blood	UBERON:0000178	53.85	gold quality
descending thoracic aorta	UBERON:0002345	53.81	gold quality
colon	UBERON:0001155	53.08	gold quality
heart left ventricle	UBERON:0002084	52.78	gold quality
multicellular organism	UBERON:0000468	52.06	gold quality
testis	UBERON:0000473	52.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.