MYCL-AS1

Summary

MYCL-AS1 (MYCL antisense RNA 1, HGNC:40386) is a long non-coding RNA gene on chromosome 1p34.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40386
Approved symbol	MYCL-AS1
Name	MYCL antisense RNA 1
Location	1p34.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236546
Ensembl biotype	lncRNA
Entrez	105378668
RNAcentral	URS00026A2533 — lncRNA, 1059 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000418255, ENST00000837551, ENST00000837552, ENST00000837553, ENST00000837554

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418255 — 3 exons

Exon	Start	End
ENSE00001647413	39898636	39899098
ENSE00004258109	39897743	39898066
ENSE00004258114	39882860	39883184

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 85.96.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.7285 / max 63.1793, expressed in 172 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
2325	0.7285	172

Top tissues by expression

99 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.96	gold quality
ganglionic eminence	UBERON:0004023	62.21	gold quality
left ovary	UBERON:0002119	57.75	gold quality
placenta	UBERON:0001987	57.19	gold quality
right lobe of liver	UBERON:0001114	56.54	gold quality
skeletal muscle tissue	UBERON:0001134	56.36	gold quality
monocyte	CL:0000576	56.29	gold quality
liver	UBERON:0002107	55.96	gold quality
vermiform appendix	UBERON:0001154	55.02	gold quality
granulocyte	CL:0000094	54.76	gold quality
urinary bladder	UBERON:0001255	54.24	gold quality
cortex of kidney	UBERON:0001225	53.99	gold quality
myometrium	UBERON:0001296	53.81	gold quality
body of pancreas	UBERON:0001150	52.67	gold quality
lymph node	UBERON:0000029	52.46	gold quality
pancreas	UBERON:0001264	52.42	gold quality
blood	UBERON:0000178	52.28	silver quality
duodenum	UBERON:0002114	52.03	gold quality
prefrontal cortex	UBERON:0000451	51.48	gold quality
bone marrow	UBERON:0002371	51.08	silver quality
stromal cell of endometrium	CL:0002255	50.92	silver quality
islet of Langerhans	UBERON:0000006	50.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.90	gold quality
uterine cervix	UBERON:0000002	49.80	silver quality
skin of abdomen	UBERON:0001416	48.14	gold quality
smooth muscle tissue	UBERON:0001135	47.51	gold quality
ovary	UBERON:0000992	47.29	gold quality
muscle of leg	UBERON:0001383	47.24	gold quality
tonsil	UBERON:0002372	47.22	gold quality
esophagus mucosa	UBERON:0002469	47.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.